To Compare the Efficacy of Dexmedetomidine, Granisetron and Tramadol in Prevention of Post-Operative Shivering In Patients Undergoing Surgeries under General Anesthesia
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 9
Abstract
Shivering is one of the major causes of distress to the patient recovering from the effects of anesthesia, both psychologically and physiologically and occurs in up to 60 % of patients recovering from general anaesthesia. Excessive shivering creates an imbalance between body's oxygen demand and supply ratio. The resultant increased demand, sometimes up to six times than normal. This study was intended to compare the efficacy of relatively newer drugs, dexmedetomidine and granisetron in reducing the incidence of postoperative shivering as compared to tramadol, which is known to be a potent antishivering agent. 90 ASA I and II patients of either sex were taken. The patients were randomly allocated into three groups, Group D Group G and Group T, comprising of 30 patients each. The patient were educated about the visual analogue scale (VAS) scale and about the drug. Any episode of shivering, fever, pain, hallucination, dry mouth, postoperative nausea and vomiting (PONV) and other complications will be recorded by a Senior Resident Anesthesia and then the data was analysed. When the patients were received in PACU in group D no patient showed shivering. Incidence of shivering in group T is 2(6.6%). Incidence of shivering in group G is 16(53.3%). The incidence of shivering in group D and group T were statistically comparable. Whereas the incidence of shivering in both group D and well as group T was statistically significantly lower than that in group G with a p value of <0.00. Dexmedetomidine 1 μg/kg is less effective than tramadol 1 mg/kg in reducing the incidence of post-operative shivering which is statistically insignificant, and granisetron is not as effective as tramadol or dexmedetomidine in reducing shivering but having an added advantage that it prevents PONV.
Authors and Affiliations
Dr. Satyendra Patidar, Dr. Shilpa Tiwari
Keywords
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