TO STUDY AHSG GENE (RS4918) POLYMORPHISM IN METABOLIC SYNDROME
Journal Title: International Journal of Medical Science and Diagnosis Research (IJMSDR) - Year 2018, Vol 2, Issue 6
Abstract
Background: Metabolic syndrome is a major public health issue of the present century. It consists of constellation of physical conditions and metabolic abnormalities Materials and methods: The present case control study was conducted in department of biochemistry, Maulana Azad Medical College in collaboration with department of medicine, Lok Nayak hospital, New Delhi. Total eighty (40 cases and 40 age and sex matched controls) fulfilling inclusion and exclusion criteria were included with their informed consent. Results: The G allele of AHSG GENE Thr256Ser C>G SNP is associated with significantly increased risk of developing metabolic syndrome. (OR:5.54,95% CI: 1.03-8.17). Conclusion: The G allele of AHSG GENE Thr256Ser C>G SNP is associated with significantly increased risk of developing metabolic syndrome Keywords: Metabolic syndrome, AHSG GENE, High density lipoproteins
Authors and Affiliations
Sarita Choudhary
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