To Study the Etiology and Predicting Scores of Patients with acute on chronic liver failure
Journal Title: Asian Pacific Journal of Health Sciences - Year 2018, Vol 5, Issue 4
Abstract
Aim: To study the aetiology, precipitating insults of patients presenting with acute on chronic liver failure and predictors of mortality of acute chronic liver failure. Methods: The prospective study was carried out in 100 patients admitted with acute on chronic liver failure for a period of 1 year in the Department of Medicine of Government medical college and Hospital, Jammu. Results: ACLF has a predominant male preponderance i.e 92 %. The mean age of patients presenting with ACLF was 45.39 ± 1.1 yrs. Among causes of chronic liver disease alcohol was commonest (79 %) followed by Alcohol + Hepatitis C (4.0 %) ,Alcohol + hepatitis B (1 %), Hepatitis B (1 %), Hepatitis C (3 %), NASH related (4 %) and Auto immune (5 %).Etiologyof acute precipitants included alcohol (43%) followed by Alcohol with Hepatitis B/C (9 %), alcohol with Hepatitis E (4%), alcohol with hepatitis E + Dengue (2%), Hepatitis E (8%), Hepatitis B (8 %) and Hepatitis C (6%) ,Hepatitis E + Leptospirosis (2%), leptospirosis (1%) and gastrointestinal bleed + others etiology (14%) were other causes of acute etiology in patients of acute on chronic liver failure. The mean SOFA, MELD and MDF scores were found to be better predictors of mortality. Conclusion: ACLF carries a high mortality rate. Alcohol was found to be the most common cause of chronic etiology of Chronic liver disease as well as acute insult. Scoring systems such as SOFA, MELD and MDF scores were considered to better predictors of mortality.
Authors and Affiliations
Rachit Magazine
Keywords
Related Articles
- EP ID EP517858
- DOI 10.21276/apjhs.2018.5.4.3
- Views 207
- Downloads 0
Teratomas in children:an institutional retrospective study
Aim and Objectives: The aim is to study the clinical presentation, malignant potential of teratomas and their management in pediatric age group. Materials and Methods: This is a retrospective study done in 52 cases of t...
Stability Indicating Simultaneous Validation of Aspirin, Clopidogrel and Rosuvastatin with Forced Degradation Behavior Study by RP-HPLC in Pharmaceutical Dosage Form
For simultaneous validating anassay of Aspirin, Clopidogrel and Rosuvastatin in Capsule Dosage Form, a simple, precise and accurate RP-HPLC method has been developed. Isocratic RP-HPLC process was established on BDS hype...
A clinical study on role of surgical management of clavicle fractures in adults
Clavicle, the horizontal bone of the body fractures is seen commonly in Road traffic accidents, fall from heights and also in simple falls. The clavicle fractures account for about 5-10% of all fractures. Traditionally i...
Role of Nutrition in the Management of Diabetes Mellitus
A healthful eating pattern, regular physical activity, and often pharmacotherapy are key components of diabetes management. For many individuals with diabetes, the most challenging part of the treatment plan is determini...
Etiology of vaginal infections and antimicrobial resistance pattern of aerobic bacterial isolates in women of reproductive age group attending a tertiary care hospital
Background: The vaginal flora is a complicated environment containing dozens of microbiological species in variable quantities and relative proportions. Many women with vaginitis may remain undiagnosed and such forms of...