To study the role of mean arterial pressure, urine calcium creatinine ratio and uterine artery Doppler between 20 -24 weeks of gestation in predicting preeclampsia
Journal Title: Indian Journal of Obstetrics and Gynecology Research - Year 2018, Vol 5, Issue 2
Abstract
Introduction Preeclampsia affects 35 of all pregnancies19 and is a leading cause of maternal morbidity and mortality 12 of all maternal deaths and also leads to perinatal consequences The initial pathological changes of preeclampsia begin in the late first trimester leading to chronic placental insufficiency Hence prediction of preeclampsia in early gestation is of great interest as early therapeutical intervention such as aspirin36 might reduce the risk of preeclampsia So in our study we aim to ascertain the role of mean arterial pressure clinical urine calcium creatinine ratio biochemical and uterine artery Doppler radiological parameters in predicting preeclampsiaAims and Objectives To study mean arterial pressure spot urine calcium creatinine ratio Doppler of uterine artery between 2024 weeks of gestational age as predictor of preeclampsia and to know the effectiveness of combination of above parameters in predicting preeclampsiaMaterials and Methods It was a prospective study involving 100 low risk pregnant women of any parity with gestational age of 2024 weeks All study individuals were followed till term and the end point of the study was considered to be the development of preeclampsia as per the ACOG criteria 2013Results All parameters mean arterial pressure urine calcium creatinine ratio and uterine artery Doppler were individually found to be statistically significant predictor Doppler of uterine artery was found to be a better predictor of preeclampsia when compared to mean arterial pressure and urine calcium creatinine ratio individually Combination of all three parameters was found to be the better predictor than individual parameterKeywords Preeclampsia Mean arterial pressure Urine calcium creatinine ratio and uterine artery Doppler
Authors and Affiliations
D. Maheswari, Prabha Ganapathy, Indira
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