Tobacco plant: A possible key to Ebola vaccine

Journal Title: Journal of Coastal Life Medicine - Year 2017, Vol 5, Issue 5

Abstract

In 2014, the World Health Organization was notified of an outbreak of a communicable disease characterized by fever, severe diarrhea, vomiting, and a high fatality rate in Guinea. Virologic investigation identified Zaire ebolavirus (EBOV) as the causative agent. Approximately 30 years after the first epidemic, there is no vaccine or therapeutic medication approved to counter the Ebola virus. In this review, it emphasized that plant based antibodies can be an effective cure to Ebola hemorrhagic fever. Genetically modified Nicotiana benthamiana is used to manufacture ZMapp drug by Kentucky BioProcessing. ZMapp three-antibody cocktail binds to the Ebola virus to deactivate it and provides simulated immune response against sugar-tagged proteins on the outside of the Ebola virus, which had verified efficacy against Ebola infection in nonhuman primates and also successfully treated two American medical workers infected with Ebola virus disease.

Authors and Affiliations

Keywords

Related Articles

The scale variation of barfi plaice Liopsetta pinnifasciata Kner, 1870 (Pleuronectidae, Pleuronectiformes)

Objective: To investigate the scales of barfin plaice (Liopsetta pinnifasciata), which depends on the size and sex of the fish. Methods: The samples were collected in Peter the Great Bay (Sea of Japan) during 2011–2014 a...

Ascaridole: A phytochemical of modern medicinal perspective

American wormseed oil, also known as Chenopodium ambrosioides oil, is obtained from the herbs of the genus Chenopodium which comprises more than 200 species and belongs to the geographical region of Asia, Europe, China,...

Toxicity of lemon grass Cymbopogon citratus powder and methanol extract against rice weevil Sitophilus oryzae (Coleoptera: Curculionidae)

Objective: To evaluate the toxicity potential of lemon grass [Cymbopogon citratus (C. citratus)] products against adult rice weevil, Sitophilus oryzae. Methods: Lemon grass (C. citratus) leaves were sundried for 7 days,...

A comparison study of the nutritional, mineral and volatile compositions of three dry forms of ginger rhizomes, and antioxidant properties of their ethanolic and aqueous extracts

Objective: To compare the most accessible dry forms of ginger rhizomes (Zingiber officinale) used as a spice and as a remedy in order to choose the best ginger for medicinal purpose. Methods: Freshly air dried ginger, co...

Seasonal abundance of Pyrodinium bahamense (order Peridiniales, family Gonyaulacaceae) in Mosquito Bay, Vieques, Puerto Rico

Objective: To determine the presence of consistent spatial or temporal patterns to the abundance of Pyrodinium bahamense (P. bahamense) in Mosquito Bay, Vieques, Puerto Rico. Methods: Measurements of dissolved oxygen, pH...

Download PDF file
  • EP ID EP236171
  • DOI 10.12980/jclm.5.2017J7-9
  • Views 126
  • Downloads 0

How To Cite

(2017). Tobacco plant: A possible key to Ebola vaccine. Journal of Coastal Life Medicine, 5(5), 206-211. https://www.europub.co.uk/articles/-A-236171