Tobacco plant: A possible key to Ebola vaccine
Journal Title: Journal of Coastal Life Medicine - Year 2017, Vol 5, Issue 5
Abstract
In 2014, the World Health Organization was notified of an outbreak of a communicable disease characterized by fever, severe diarrhea, vomiting, and a high fatality rate in Guinea. Virologic investigation identified Zaire ebolavirus (EBOV) as the causative agent. Approximately 30 years after the first epidemic, there is no vaccine or therapeutic medication approved to counter the Ebola virus. In this review, it emphasized that plant based antibodies can be an effective cure to Ebola hemorrhagic fever. Genetically modified Nicotiana benthamiana is used to manufacture ZMapp drug by Kentucky BioProcessing. ZMapp three-antibody cocktail binds to the Ebola virus to deactivate it and provides simulated immune response against sugar-tagged proteins on the outside of the Ebola virus, which had verified efficacy against Ebola infection in nonhuman primates and also successfully treated two American medical workers infected with Ebola virus disease.
Marine soft corals as source of lead compounds for anti-inflmmatories
Marine soft corals are known to produce a wide array of secondary metabolites, particularly diterpenoids and steroids, and often characterized by uncommon structural features and potent bioactivities. The remarkable abun...
First record of Necrobia rufipes (De Geer, 1775) (Coleoptera: Cleridae) from Khuzestan Province, southwest of Iran, a beetle species of forensic importance
Objective: To introduce Necrobia rufipes as a forensic important species in the study area. Methods: This study was performed using a laboratory bred rat (Wistar rat) weighing 352 g as a model for decomposition. The rat...
Impact of ginger aqueous extract on carbimazole induced testicular degenerative alterations and oxidative stress in albino rats
Objective: To evaluate the effect of ginger (Zingiber officinale) aqueous extract, a natural herb, with antioxidant properties, on testicular toxicity and oxidative stress induced by the antithyroid drug carbimazole in a...
Description of an eye barotrauma in scuba diving with clinical discussion
In this paper we report and discuss a scuba diving accident caused by compression of the mask at a depth of 9.1 m resulting in conjunctiva haemorrhage of both eyes in a 21-year-old male. After five weeks and benefiting f...
Early weaning of yellowtail amberjack Seriola lalandi dorsalis (Gill 1863) larvae
Objective: To understand the effect of weaning time on the rearing performance of yellowtail amberjack Seriola lalandi dorsalis in the experimental condition. Methods: The same weaning protocol started on four different...