Toxicity Study of Textile Effluent of Udhna, Surat Region (Gujarat) on Wistar Albino Rat
Journal Title: Universal Journal of Environmental Research and Technology - Year 2015, Vol 5, Issue 1
Abstract
The Sub-acute oral toxicity study was designed and conducted to determine the toxicity profile of Textile Effluent Sample (SR1) when administered by oral route daily for 28 days to wistar albino rat. Effluent sample (SR1) was collected from Textile industry of Udhna, Surat. Textile Effluent Water Sample (SR1) dissolved in distilled water was administered to Rat by oral route at the dose levels of 0 mg/kg to 20 ml/kg i.e. 0 mg/kg, 2.5 ml/kg, 10 ml/kg and 20 ml/kg body weight. Histopathology, Hematological and serum Biochemical study were carried out on wistar albino rat. In this study, body weight and food consumption decreased in the 10.0 and 20.0 ml/kg dose groups, and hepato cellular hypertrophy and minimal bile duct proliferation were found at a higher incidence in animals in the 20.0 ml/kg dose group, while inflammation of the prostate were recorded at a higher incidence in the 10.0 and 20.0 ml/kg dose groups. In Textile Effluent Sample (SR1) treated groups, serum triglyceride level decrease significantly. The No Observed Adverse Effect Level (NOAEL) of Textile effluent (SR1) was considered to be 2.5 ml/kg body weight/day.
Authors and Affiliations
Kanthariya Bhavesh V. and Tank S. K.
Keywords
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