Toxicological and Hygienic Characteristics of Astarg 125 EC Herbicide
Journal Title: Український журнал сучасних проблем токсикології - Year 2017, Vol 80, Issue 4
Abstract
Objectives of the work. To study the toxicity of the quizalofop-p-ethyl technical generic, toxicological and hygienic properties of the agent Astarg 125 EC (quizalofop-p-ethyl, 125 g/L) made on its basis, and to develop the regulation of the application of this herbicide in agriculture. Methods of the study. Toxicological, hygienic, chemical and statistical. Results and their discussion. The toxicity parameters of the quizalofop-p-ethyl generic and Astarg 125 EC herbicide made on its basis were determined using different routes of exposure to laboratory animals. The conducted studies showed that the character of the toxic effect and the non-effective level of quizalofop-p-ethyl do not significantly differ from those of compounds produced by other companies that are registered in Ukraine. According to the toxicity indicators, quizalofop-p-ethyl and Astarg 125 EC herbicide refer to pesticides of the 2nd hazard class (State Sanitary Rules and Regulations 8.8.1.002-98). Limiting harmful index is inhalation toxicity. The species sensitivity of laboratory animals to toxic effect was not observed. The results of the hygienic assessment of working conditions when using Astarg 125 EC herbicidal agent under agricultural production conditions showed that when assessing the conditions for its safe use, it is necessary to take into account the hygienic standards in the working zone air and open air of the inhabited areas of its active ingredient — quizalofop-p-ethyl. Conclusions: - Taking into account quizalofop-p-ethyl content level in the herbicide Astarg 125 EC, its toxicity parameters at different routes of exposure, it is possible to use it for its intended purpose provided that the regulations for safe use, as well as the usual precautions for storage and application of the agent are observed. - Using Astarg 125 EC to protect sugar beet is safe from the standpoint of nutrition hygiene. It is recommended to use the herbicide on sugar beet with a consumption rate of 1,2 L/ha. - Control of the aerial environment and environmental objects when applying Astarg 125 EC herbicide should be carried out according to its active ingredient — quizalofop-p-ethyl.
Authors and Affiliations
V. M. Voronina, V. S. Mykhajlov, A. P. Grinko, N. V. Kolontaeva
Keywords
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