Traditional Chinese medicine treatment of immune-related pneumonia caused by PD-1/PD-L1 inhibitors
Journal Title: TMR Clinical Research - Year 2020, Vol 3, Issue 2
Abstract
With the wide application of immunotherapy drug PD-1/PD-L1 inhibitor in China and the continuous clinical research, a major problem that we have to face is the immune-related pneumonia caused by PD-1/PD-L1. At present, western medicine mainly treated it by hormone therapy, which may cause side effects, such as obesity, osteoporosis and osteonecrosis for hormone therapy by long-term, and increase the patients' pain. Under the guidance of the theory of syndrome differentiation, traditional Chinese medicine (TCM) advocates the methods of expelling wind and clearing away cold, resolving phlegm and relieving asthma, relieving heat from lung, and invigorating the spleen and tonifying the kidney, etc. Exact differentiation of symptoms and rational usage of drugs can play an important role in the early prevention and treatment of immune-related pneumonia, reflecting the important role of TCM in the prevention and treatment of side effects of new drugs. In order to provide an effective clinical reference for clinicians in the practice of using PD-1/PD-L1, this paper systematically reviewed the use of TCM in the treatment of immune-related pneumonia induced by PD-1/PD-L1 inhibitors.
Authors and Affiliations
Xun Sun, Bing Dai, Liang Lei
Keywords
Related Articles
- EP ID EP683401
- DOI 10.12032/TMRCR20200419006
- Views 193
- Downloads 0
Explore the mechanism and treatment analysis of Acupuncture and Moxibustion for Constipation after Stroke
Modern research has shown that there is a special brain-gut axis between the brain and the gut, which can regulate and maintain the stable function of the body. Many studies have also proved that acupuncture at certain a...
Construction of an intelligent patient satisfaction assessment system and its application in emergency management
Hospital emergency management work is of great importance which not only related to the life and health of the people but also related to social stability. It is necessary to construct and improve the patient satisfacti...
Evaluation of autophagy-related genes and lncRNAs signature for prognositic prediction in thyroid carcinoma via bioinformatics analysis
Autophagy plays a significant role in the pathogenesis and prognosis of thyroid carcinoma. The role of autophagy-related genes and long non-coding RNAs, as well as the risk model of thyroid carcinoma patients were in...
Screening of acupuncture treatment for simple obesity
Objective: Observe the advantages and characteristics of Acupuncture therapy and Point Thread Embedding therapy in the treatment of simple obesity and to select the superior treatment schemes. Methods: on the basis of...
Insight into the post-hospital syndrome
After hospitalization, the patient faces a brief fragile period of susceptibility to disease and a high incidence of adverse events (re-admission or death, etc.), which is described by cardiologist Harlan M.Krumholz as p...