Trans Nasal Butorphanol for Post Operative Analgesia in Lower Abdominal Laparoscopic Surgeries
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 7
Abstract
Background: Postoperative pain is acute with complex physiological responses to tissue injury. Trans nasal Butorphanol has been found to provide better pain relief and also decreased incidence of postoperative complications. Aim: This study was done to know onset, duration, quality of analgesia, cardio-respiratory effects and side effects of Transnasal butorphanol for the relief of postoperative pain in lower abdominal laparoscopic surgery Methods A total of 60 patients of females, belonging to 20-60 yrs of age, ASA grade I and II admitted for lower abdominal laparoscopic surgeries were selected randomly for the study. Patients were divided into 2 groups as 30 each Group A- Butorphanol 1mg nasal spray, Group B- normal saline nasal spray was used as the study drugs for the relief of postoperative pain. Onset of analgesia, Duration of analgesia, Quality of analgesia, Level of consciousness, Cardio-respiratory effects, Side effects were recorded. Results :In our study the mean time of onset of analgesia in Butorphanol group (group-A) was 11.3±2.25 (SD) min and the duration of action of analgesia was 4.86±1.02 (SD) hrs which are statistically significant, Quality of Analgesia (VAS) was good, with majority of the patients grading their pain relief as excellent. Sedation score was maximum at 30 mins after administration later there was gradual decrease in sedation score due decrease in analgesic action of Butorphanol. Incidence of side effects like nausea and vomiting were also negligible. No significant respiratory depression was seen in either group. Conclusion: Transnasal Butorphanol spray is a safe and efficacious drug for post-operative analgesia. It provides a rapid, excellent but shorter duration of analgesia. It has mild sedation which is advantageous in the postoperative period.
Authors and Affiliations
Abhimanyu Singh
Keywords
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