Treatment modalities and visual prognosis of polypoidal choroidal vasculopathy with breakthrough vitreous hemorrhage
Journal Title: Eye Science (Yanke Xuebao) - Year 2022, Vol 37, Issue 8
Abstract
Polypoid choroidal vasculopathy (PCV) is a common fundus blinding disease in Asians. When PCV is associated with subretinal hemorrhage or vitreous hemorrhage (VH), patient's visual acuity decreases suddenly and the visual prognosis varies greatly. There are few relevant literatures focusing on VH secondary to PCV, so it is of great clinical significance to study and clarify the treatment methods and prognosis of VH secondary to PCV. At present, surgical intervention is often selected in clinical practice. Vitrectomy is the most commonly selected surgical procedure in clinical practice. The other treatment modalities include intravitreal injection of anti-vascular endothelial growth factor (VEGF), intraocular gas or silicone oil filling, intraocular injection of tissue plasminogen activator (tPA) and photodynamic therapy. The prognostic determinant of visual acuity in PCV patients with VH is the degree of preservation of macular visual function. The prognostic is also related to age, preoperative visual acuity, PCV lesion location, amount of subretinal hemorrhage, extent of retinal detachment, baseline central macular thickness (CMT), postoperative complications and retinal scars. Recent studies also find that the prognosis of visual acuity is related to single nucleotide polymorphisms. This article reviews the clinical characteristics, treatment and visual prognosis of PCV associated with VH.
Authors and Affiliations
Chenxi CAI, Qiang WANG, Xinhua HUANG, Tao LI, Yonghao LI, Bingqian LIU, Ying LIN, Lin LÜ
Keywords
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- EP ID EP763713
- DOI 10.3978/j.issn.1000-4432.2022.06.13
- Views 13
- Downloads 0
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