TREATMENT OF COLORECTAL CANCER: ACTUAL STRATEGIES AND PROMISING PERSPECTIVES
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2018, Vol 7, Issue 8
Abstract
In the US, colorectal cancer (CRC) is the third most frequent type of cancer and the third cause of mortality related to cancers. Actual treatment strategies consist of surgery as the only curative therapy for early stages, adjuvant chemotherapy as a standard option for stage III disease, biologic agents in combination with chemotherapy regims for metastatic disease and palliative care for untreatable diseases. Today, the 5-year survival rate for stage IV of CRC is around 10% and this is why we must find solutions to improve survival rates for advanced stages. Some of the new promising perspectives for the treatment of advanced stages of CRC are represented by intracellular anti-EGFR agents, stimulation of the anti-tumor immunity and the use of nanotechnologies for targeted ablation or as a delivery system for siRNA.
Authors and Affiliations
Dr. Sur G. Daniel
Keywords
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