Tuberculosis Among Household Contacts of Multidrug-Resistant Tuberculosis Cases at a Tertiary Hospital in Lucknow, India
Journal Title: SSR Institute of International Journal of Life Sciences (SSR-IIJLS) - Year 2018, Vol 4, Issue 2
Abstract
Background- Multidrug-resistant tuberculosis (MDR-TB) is caused by strain of Mycobacterium tuberculosis, it is transmitted through air droplets from infected person and close contacts of MDR-TB patients have a high potential to developing TB. This study aims to determine the profile of TB/multidrug-resistant TB (MDR-TB) among household contacts of MDR-TB patients. Methods- The cases were recruited from the King George’s Medical University, Lucknow, India. In this cross-sectional study, close contacts of MDR-TB patients were screened for tuberculosis, clinical, radiological and bacteriological experiments were performed to find out the evidence of TB/MDR-TB. Results- The cases were enrolled between December 2015 to December 2016, total of 100 index MDR-TB patients were recruited, which initiated on MDR-TB treatment. A total of 428 contacts, who could be studied, 11 (2.57%) were diagnosed with MDR-TB and 4 (0.93%) had TB. The most frequent symptoms observed in patients were cough, chest pain and fever. Conclusion- Tracing symptomatic contacts of MDR-TB cases could be a high yield strategy for early detection and treatment of MDR-TB cases to contribute to reduced morbidity, mortality and to cut the chain of transmission of infection in the community. The approach should be bringing about for wider implementation and dissemination.
Authors and Affiliations
Rajeev Kumar, RAS Kushwaha, Amita Jain, Zameerul Hasan, Priyanka Gaur, Sarika Panday
Keywords
Related Articles
- EP ID EP671160
- DOI 10.21276/ijlssr.2018.4.2.16
- Views 124
- Downloads 0
EGFR Mutation and Tyrosine-Kinase Inhibitors (TKI) in Non Small Cell Lung Cancer: An Overview
Lung cancer is the most common cause of cancer related mortality worldwide. The epidermal-growth-factor receptor (EGFR) cascades the signaling pathway that regulates tumor-cell proliferation, invasion, angiogenesis, meta...
Isolation, Identification and Screening of Alkaline Protease from Thermophilic Fungal Species of Raipur
Proteases are protein degrading enzymes that catalyses hydrolytic reaction in which protein molecules are degraded into peptides and amino acids. Thermostable alkaline proteases are of particular great interest for indus...
Biosynthesis of Copper Nanoparticles using Artocarpus heterophyllus against Dengue Vector Aedes aegypti
In our present study, we accounted for eco-friendly biosynthesis of copper nanoparticles using aqueous leaves extract of Artocarpus heterophyllus against first to fourth instar larvae of Aedes aegypti. The synthesized Cu...
Studies on Population Characteristics of Frigate tuna, Auxis thazard (Lacepede,1800) Occurring in the North West Coast of India
This study is an attempt to understand the population characteristics such as Length-weight relationships, age, growth, mortality, length at age and exploitation rate of Frigate tuna, Auxis thazard occurring in the North...
Effect of pH and Temperature on Secondary Metabolite Isolated from Soil Bacteria
Secondary metabolites used to treat infections caused by microbial pathogens. It can cause illness to humans and animals. This study was carried out to screen for potential antimicrobial producing microbes from soil samp...