Tuberculous meningitis: symptoms, diagnosis and evaluation experienced in 532 patients in a pediatric hospital
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2016, Vol 6, Issue 3
Abstract
Objective: To analyze the procedures to manage tuberculous meningitis (TM) employed in a third level hospital. Methods: A descriptive study was carried out on the procedures used to manage TM in 532 children attended at the Infectology Service of National Institute of Pediatrics of Mexico City. Patients included must have analysis of cerebrospinal fluid suggestive of TM and negative for other bacteria among others criteria. Results: The predominant signs observed were fever in 486 patients, apathy in 485, somnolence in 477, headache in 173, seizure crisis in 400 and coma progression in 17. Cerebrospinal fluid showed an average of 199 cells/mL, proteins 170.8 mg. Chest X-ray showed abnormalities in 330 cases and brain tomography revealed basal arachnoiditis in 306 cases. 24 patients died and 414 of them had audition and epileptic sequels. Conclusions: TM has continued to be a serious health problem in developing countries. Delay in diagnosis of this disease is a cause of the increase not only of its morbidity but also its mortality as well as its sequels.
Phytochemical screening, antioxidant activity and analgesic effect of Waltheria ovata Cav. roots in mice
Objective: To determine the phytochemical screening, antioxidant activity and analgesic effect of crude ethanol extract of Waltheria ovata (W. ovata) Cav. root in mice. Methods: Phytochemical screening was developed by c...
Efficacy of Stigmast-5-en-3β -ol Isolated from Salvadora persica L. as Antihyperlipidemic and Anti-tumor agent: Evidence from animal studies
Objective: To explore the anti-hyperlipidemic and anti-tumor effect of ethanolic extract, chloroform fraction and stigmast-5-en-3毬 -ol from stems of Salvadora persica L. Methods: The antihyperlipidemic effect of ethanol...
Molecular investigation of sub-microscopic and mixed Plasmodium species infection in North-Central Nigeria
Objective: To assess the level of sub-microscopic and mixed Plasmodium species infection in children in North-Central Nigeria. Methods: Blood sample was obtained from 960 apparently healthy children aged 2–18 years. Plas...
Socio demographic wise risk assessment of thyroid function abnormalities in far western region of Nepal: A hospital based descriptive study
Objective: To know the status of thyroid disorder in population of far western region of Nepal. Methods: A total of 808 cases (1 33 men and 675 non pregnant women) were included and study was carried out using data retri...
Assessment of an ELISA for serodiagnosis of active pulmonary tuberculosis in a Cuban population
Objective: To explore the serodiagnostic potential of the five recombinant Mycobacterium tuberculosis antigens CFP-10 (Rv3874), ESAT-6 (Rv3875), APA (Rv1860), PstS-1 (Rv0934), Ag85A (Rv3804c) and their combination in a C...