Tumor lysis syndrome
Journal Title: OncoReview - Year 2012, Vol 2, Issue 2
Abstract
Tumor lysis syndrome is a life-threatening oncological emergency occurring in response to chemotherapy or spontaneously as a result of massive and rapid breakdown of malignant cells. The release of their contents into circulation leads to a constellation of the characteristic metabolic abnormalities (hyperuricemia, hyperphosphatemia, hyperkalemia, hypocalcemia) and their clinical consequences such as acute bkidney injury, cardiac arrythmias and death. The article summarizes the current knowledge on tumor lysis syndrome prophylaxis and treatment.
Authors and Affiliations
Joanna Matuszkiewicz-Rowińska, Mariusz Mieczkowski
Keywords
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