UNDERSTANDING THE PREVALENCE OF DEPRESSION IN PREGNANT WOMEN WITH GESTATIONAL DIABETES MELLITUS AND ITS ASSOCIATION WITH METABOLIC PROFILE
Journal Title: INTERNATIONAL JOURNAL OF ADVANCED MEDICINE - Year 2019, Vol 3, Issue 3
Abstract
Introduction- Previous literature suggest that there exists a bi-directional relationship between diabetes and depression. But the evidence about the prevalence of depression in pregnant women with gestational diabetes mellitus in India and its co-relation with the sugar laboratory prole and anthropometrics is scanty. Objectives- To study the prevalence and association of depression during pregnancy with GDM , and to analyse and associate the metabolic parameters like BMI, Glucose tolerance and BP with depression in GDM patients. Methodology-In this cross-sectional analytical study, done at the obstetrics OPD of a hospital, on 347 antenatal cases(gestational age > 24 weeks), sociodemographic details, BP,BMI,Blood Sugar(OGTT) were measured.For depression status's assessment, CUDOS(Clinically Useful Depression Outcome Scale)Questionnaire used.Data analyzed by SPSS 23. Results- In our study, signicant difference was found in prevalence of depression in GDM patients(56.07%) and Non-GDM Subgroup( 38.5%).And GDM subgroup had more number of women with mild and moderate depression.Mean Depression Score was 14.7 and 9.5 in GDM and Non-GDM groups, respectively. Also, Depression and GDM were found to be signicantly associated.GDM group was found to have more mean age(GDM with depression=27.5 and Non-GDM without depression=24.9).Also, GDM aged more than 30 were more prone to develop depression.GDM women with depression had more mean BMI(27.14) vs. GDM without depression(25.03). BMI was signicantly associated with the depression in the GDM population.Mean OGTT values were higher among the women who had depression and the difference was signicant for the 1hr and 2hr blood glucose sample.We found that there is a signicant association betweenthe deranged OGTT valuesabove diagnostic cutoff of GDM and the depressionamong GDM population. GDMsub-group chiey consisted of women with middle and highsocio-economic group. Conclusion- Early screening for depression in GDM patients must be done, to manage the diabetes well and prevent the development of complications. As this will prove benecial for the physiological and psychological condition of the patient.
Authors and Affiliations
Dr Amitabh Saha, Mr Aditya Rana, Dr VV Gantait
THE THERAPEUTIC EFFECTS OF TAURINE AGAINST HEPATOTOXICITY INDUCED THROUGH CARBON TETRA CHLORIDE IN RATS
The present study explores the protecting functions of Taurine on lipid-peroxidation and antioxidant enzymes' activity in Carbon tetrachloride induced liver brosis and cirrhosis in experimental rat models. Study include...
GITELMAN SYNDROME AS A CAUSE OF PSYCHOMOTOR RETARDATION IN A TODDLER
Introduction: Gitelman syndrome (GS) is a very rare autosomal recessive tubulopathy due to loss-of-function or mutation in solute carrier family12, member 3 gene (SLC12A3 gene) encoding thiazide-sensitive NaCl co- transp...
EVALUATION OF RISK FACTORS AND RISK VARIATIONS AMONG CARDIOVASCULAR AND NON CARDIOVASCULAR DISEASE PATIENTS.
BACKGROUND AND OBJECTIVES: Heart diseases are one of the leading causes for death in Indian population but, majority is due to lack of awareness and proper prediction. Main objective is to evaluate risk factors and risk...
A CASE OF SPONTANEOUS KLEBSIELLA PNEUMONIA VENTRICULITIS FOLLOWING LEFT BASAL PNEUMONIA
We report a case of 35 year old male brought with a history of fever, headache and blurring of vision since three days. On examination, he had neck rigidity and bilateral crepts on auscultation with decreased air entry o...
A CROSSSECTIONAL STUDY OF SEXUAL DYSFUNCTION IN ALCOHOLIC MALES
Background: chronic alcoholism is known to induce sexual dysfunction but most studies lack in determining the type of sexual dysfunction and its clinical correlation. Objective: We attempted to assess the sexual dysfunct...