Use of MicroRNAs to Screen for Colon Cancer
Journal Title: Insights in Biology and Medicine - Year 2017, Vol 1, Issue 1
Abstract
Colon cancer (CC) screening is important for diagnosing early stage for malignancy and therefore potentially reduces mortality from this disease because the cancer could be cured at the early disease stage. Early detection is needed if accurate and cost effective diagnostic methods are available. Mortality from colon cancer is theoretically preventable through screening. The Current screening method, the immunological fecal occult blood test, FOBTi, lacks sensitivity and requires dietary restriction, which impedes compliance. Moreover colonoscopy is invasive and costly, which decreases compliance, and in certain cases could lead to mortality. Compared to the FOBT test, a noninvasive sensitive screen that does not require dietary restriction would be more convenient. Colonoscopy screening is recommended for colorectal cancer (CRC). Although it is a reliable screening method, colonoscopy is an invasive test, often accompanied by abdominal pain, has potential complications and has high cost, which have hampered its application worldwide.
Authors and Affiliations
Farid E Ahmed, Nancy C Ahmed, Mostafa Gouda, Chris Bonnerup
Keywords
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- EP ID EP556874
- DOI 10.29328/journal.hjbm.1001006
- Views 46
- Downloads 0
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