Usefulness of Transbronchial Cryobiopsy in Interstitial Lung Disease
Journal Title: Archives of Pulmonology and Respiratory Care - Year 2017, Vol 3, Issue 2
Abstract
Interstitial lung disease (ILD) is a term that describes a group of more than 200 lung disorders that show varying degrees of inflammation and fibrosis of the pulmonary interstitium. The etiology and pathophysiology of many of these disorders still remains poorly understood and is the topic of ongoing research and debate. The diagnostic approach to ILD can be complex and often requires a multidisciplinary team approach with involvement of a pulmonologist, radiologist and pathologist. A lung biopsy is often needed to determine the particular subcategory of interstitial lung disease. Unfortunately, conventional transbronchial biopsy with forceps has a very poor diagnostic yield in ILD. A large review of 801 patients showed a diagnostic yield of less than 30% [1]. Surgical lung biopsy is considered the “gold standard” but has a high mortality with several studies showing a mortality of 1.7% to 4.2% in elective cases and 16% to 17.5% in urgent cases [2-6]. In the last several years, the introduction of bronchoscopic transbronchial cryobiopsy has been an exciting development in this regard. This particular diagnostic intervention has the potential to provide diagnosis in ILD with a safety profile closer to conventional transbronchial biopsy and a diagnostic yield approaching surgical lung biopsy.
Authors and Affiliations
Gauhar Umair A
Keywords
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- EP ID EP340902
- DOI 10.17352/aprc.000025
- Views 61
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