Using Antibiotic loaded bone cement (ALBC) as the novel method to treatment of chronic osteomyelitis
Journal Title: Scholars Journal of Medical Case Reports - Year 2016, Vol 4, Issue 12
Abstract
Bone and joint infection is the main complication of bone fracture as a result of pyogenic bacteria. The long-term clinical course, extended period of silence, cases of recurrence and abundant discharge are the overriding side effects of bone infection that can be considered a challenge to treat the patients. Given the associated problems of bone infection, the aim of current study is to elucidate the efficiency of Antibiotic loaded bone cement (ALBC) as the novel method to treatment of chronic osteomyelitis. This study looks at the treatment of chronic osteomyelitis through cement containing antibiotic approach. Five patients with chronic osteomyelitis as a consequence of surgical operation of bone fracture were evaluated for efficiency of ALBC method (Gentamicin and Vancomycin have been used as antibiotics in our homemade bone cement). The study was performed in Imam Khomeini hospital of Falavarjan in Isfahan between February 2009 to January 2014. The patient information was obtained from the hospital data bank to monitor treatment and recovery. The ALBC application in temporary manner leads to magnificent results about treatment of chronic osteomyelitis and septic arthritis. However, extensive and complete debridement of necrosis and infectious area with application of proper fixation and bone graft should be considered with the ALBC. Our results have shown that antibiotic loaded cement leads to reduction of pyrogenic discharge as the main clinical complication of chronic osteomyelitis in all patients also; the application of extensive debridement and antibiotic drugs is declined. It should be noted that the patient satisfaction was increased by this approach. Finally, the cement-containing antibiotic can be suitable approach to reduce bone infection. Keywords: Cement-containing Antibiotic, Chronic Osteomyelitis, Bone Fracture.
Authors and Affiliations
Reza Babaei, Hooman Shariatzadeh
Keywords
Related Articles
- EP ID EP374291
- DOI -
- Views 97
- Downloads 0
Inflammatory Pseudotumor Occurring at a Rare Site - Female Pelvic Cavity- A Case Report
Abstract:Inflammatory pseudotumor is a quasineoplastic lesion consisting of inflammatory cells and myofibroblastic spindle cells. Inflammatory pseudotumor most commonly involves the lung and the orbit, but it has been re...
Intraosseous Synovial Cyst of the Scaphoid about a Case with Review of the Literature
The intraosseous synovial cyst is a benign bone tumor of the osteolytic type; it usually develops in the epiphyses of the long bones. Its location on carp bones is rare. We report here the case of a woman of 34 who consu...
Unilateral proptosis veiling aggressive tumour
Out of all the brain tumours, meningiomas account for 15% of the total share and Sphenoid ridge is the third commonest site,though in children, only 4.2-15% of intracranial meningiomas involve the sphenoid wing.A case o...
Utilization of ultrasound in diagnosing Heterotopic Pregnancy
A heterotopic pregnancy is a rare complication of pregnancy in which both extra-uterine (ectopic pregnancy) and intrauterine pregnancy occur simultaneously. It may also be referred to as a combined ectopic pregnancy, mul...
Haemolytic Anemia with Peripheral Gangrene a Rare Duo of Cold Agglutinin Disease
Primary cold agglutinin disease is usually associated with monoclonal cold-reacting auto antibodies. Disease is chronic and occurs after the fifth decade of life, with a peak incidence in the seventh and eighth decades....