Using Hippophae rhamnoides leaf extract in the treatment of chicken pox in children
Journal Title: Актуальна інфектологія - Year 2018, Vol 6, Issue 2
Abstract
Background. In Ukraine, about 150 thousand children suffer from chicken pox every year. Symptomatic and supportive treatment is indicated for all forms of chicken pox. The purpose of the study was to evaluate the efficacy and tolerability of Hippophae rhamnoides (Erebra) extract in the comprehensive treatment of chicken pox in children. Materials and methods. Research design: prospective, open-label, controlled. The study involved children who underwent inpatient treatment with a diagnosis of chicken pox during 2017–2018. Patients in the main group received Hippophae rhamnoides extract in the combined treatment of chicken pox, standard symptomatic therapy was prescribed to control patients. Results. Sixty four children were examined, the main group consisted of 34 patients, control group — 30 individuals. On the background of therapy, a positive dynamics of clinical symptoms was observed in all patients. On day 5, fever was more frequently detected in controls than in the main group (50.0 vs 23.5 %, p < 0.05 according to the χ2 criterion). Disorders of the general state on day 3 of observation were noted in 55.8 % of children in the main group and in 86.7 % of controls (p < 0.05 according to χ2 criterion). Conclusions. The use of Hippophae rhamnoides extract in comprehensive therapy of children with chicken pox accelerates the normalization of clinical symptoms. The Hippophae rhamnoides extract has a high safety profile and is well tolerated.
Authors and Affiliations
S. O. Кramarov, V. V. Yevtushenko, V. O. Shadrin, E. V. Golovach, Т. M. Kaminskaya
Determination of the Quantitative Content of HBsAg in Blood Serum during Complex Monitoring for Chronic Hepatitis B in HIV-Infected Patients
The paper presents the results of quantitative content of HBsAg investigation in patients with HIV/chronic hepatitis В coinfection compared with the presence/absence of hepatitis В virus DNA and alanine aminotransferase...
Oxidative Stress in Patients with HIV-Infection
In the study we investigated the frequency and depth of liver injury in patients with acquired immunodeficiency syndrome, depending on age, sex, duration of disease, effects of highly active antiretroviral therapy (HAART...
Features of Clinical and Biochemical Parameters and Indicators of Neurohumoral Regulation in Patients with Chronic Hepatitis C and Mixed Cryoglobulinemia Depending on the Infection with Different HCV Genotypes
Purpose. To identify the features of clinical and biochemical parameters and indicators of neurohumoral regulation in patients with chronic hepatitis C and mixed cryoglobulinemia depending on the infection with different...
Influenza Vaccination in Patients with Diabetes Mellitus Type 1
This study assessed influenza vaccination coverage in children with diabetes mellitus type 1 in various epidemiological periods. Data were delivered from vaccination histories of 325 patients aged 7–18 years for a period...
Infectious diseases related to earthquakes
The article deals with a review of literature on infectious diseases, increased incidence of which was associated with earthquakes.