Uterine Myxoid Leiomyosarcoma with Paraneoplastic Syndrome- A Rare Combination
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 1
Abstract
Myxoid leiomyosarcoma of uterus is a very rare malignancy with only 36 cases documented worldwide and no cases reported in the Indian subcontinent. The present case is of uterine myxoid leiomyosarcoma with associated pancytopenia that has not been described previously in the south-east asia and only one such case reported in world literature. A 32 year old woman who is a known case of uterine fibromyoma discovered in her previous pregnancy , presented to the opd with heavy bleeding per vagina. On examination, she had a large abdominal mass. Her hemoglobin was 6.3 g/dl and platelet count was 80,000/cu.mm and also developed leucopenia(4500/cu.mm).She had received five units of blood transfusion, but her haemoglobin and platelet counts remained low. Her bone marrow biopsy report came out to be inconclusive. She underwent laparotomy followed by total hysterectomy with bilateral salphingoophorectomy, omentectomy and appendicectomy. Histopathology reports showed uterine myxoid leiomyosarcoma ( FIGO stage IIIA). Her haematological profile improved considerably following the surgery and recurred with the recurrence of the disease. Hence, this is considered to be a case of pancytopenia due to paraneoplastic syndrome as a result of the myxoid leiomyosarcoma of the uterus.
Authors and Affiliations
Dr. Shubhadeep Bhattacharjee
Keywords
Related Articles
- EP ID EP210493
- DOI -
- Views 101
- Downloads 0
Malnutrition in Children with Cerebral Palsy: An Indian Study
Cerebral palsy is the commonest neurological disorder of childhood associated with significant motor impairment. The children with cerebral palsy are found to have poor growth. Poor caloric intake and difficulty in feedi...
Scrub Typhus with a Rare Presentation in a Child- A Case Report
Acute kidney injury (AKI) due to infections is an important preventable cause of morbidity and mortality in the tropical region. The prevalence and outcome of AKI in children with scrub typhus is not known. We report a c...
Salmonella Entericaserovars Showing Resistance to Azithromycin in A Tertiary Care Hospital From South India
Introduction Enteric fever is an important public health problem caused by salmonella species (typhoidal group) Salmonella enteric serovar typhi, Paratyphi A, Paratyphi B and Paratyphi C. WHO estimates 21.7 million cases...
Evaluation of Urinary Albumin Level in Newly Diagnosed Hypertensive Patients for Early Digonosis of Renal Diseases in Rural Area of Rajasthan
Now-a-days, Hypertension is worldwide threat. For the detection of early renal disease, proteinuria play the important role. Specially, urine albumin is important to find out early renal diseases. For the present study,...
Cardiovascular effects of methylphenidate in children with attention deficit hyperactivity disorder (ADHD)
The present study was conceived with the objective to examine the effects of methylphenidate on cardiovascular variables in children with Attention-deficit/hyperactivity disorder (ADHD). ECG indices plus systolic blood p...