Variation in 1(3S) and 2(2S) rejections incidence in internal quality control program on using 20 reading mean and SD of different periods
Journal Title: International Journal of Biomedical and Advance Research - Year 2015, Vol 6, Issue 11
Abstract
Objectives: Objective of the study is to measure dispersion of 1(3S) and 2(2S) rejection incidence in six month period using mean and SD derived from 20 readings of different periods of internal quality control program. Material & Method: Data collected from LIS were analyzed in computerized spreadsheet. For various 20 reading slots, mean and SD were calculated. They were used to find 1(3S) and 2(2S) rejection incidences for each set of mean and SD. Result & Discussion: By using 20 reading SD and mean of different period, Incidence of 1(3S) rejection varied from 0-17 percent for ALT, 0-4 percent for ALB, 0-38 percent for GLC, 0-4 percent for TBIL, 0-2 percent for DBIL, 0-10 percent for CR, 0-40 percent for Na, 0-61 percent for K, 0-21 percent for URE, 0-16 percent for TP. Incidence of 2(2S) rejection varied from 0-16 percent for ALT, 0-9 percent for ALB, 0-19 percent for GLC, 0-2 percent for TBIL, 0-2 percent for DBIL, 0-6 percent for CR, 0-17 percent for Na, 0-25 percent for K, 0-11 percent for URE, 0-15 percent for TP. Conclusion: Use of 20 data points for calculation of SD and Mean for new lot of QC sera, as suggested by CLSI C24-A2 results in wide variation in 2(2S) and 1(3S) rejection incidences. New SD and mean should be calculated as soon as larger data set is available.
Authors and Affiliations
Khushbu Soni, Riddhiben Rajendrakumar Patel, Shailesh Manubhai Patel, Sarita Jagadishbhai Mangukia
Keywords
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- EP ID EP355372
- DOI 10.7439/ijbar.v6i11.2691
- Views 85
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