Vasopressin and Terlipressin for Pediatric Refractory Shock
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 2
Abstract
Objective: To review the physiology and the published literature on the role of vasopressin in shock in children. Results: Beneficial effects have been reported in vasodilatory shock and asystolic cardiac arrest in adults. Solid evidence for vasopressin use in children is scanty. Observational studies have reported an improvement in blood pressure and rapid weaning off of catecholamines during administration of low-dose vasopressin. Dosing in children is extrapolated from adult studies. Conclusions: Vasopressin offers promise in shock and cardiac arrest in children. However, in view of the limited experience with vasopressin, it should be used with caution. Results of a double blind, randomized controlled trial in children with vasodilatory shock will be available soon.
Authors and Affiliations
Dr Pradeep Kumar
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