Vitamin D status and bone turnover marker levels in Greek women with fragility hip fracture
Journal Title: International Journal of Orthopaedics Sciences - Year 2017, Vol 3, Issue 1
Abstract
There is little data regarding Vitamin D deficiency in Greece. Also conflicting are the data regarding the bone turnover during the acute hip fracture interval and the situation is even more complex considering the recently developed bone turnover markers (BTMs). The aim of this study was to evaluate the parameters of bone mineral homeostasis of women with fragility hip fracture using the recently developed BTMs of carboxy-terminal collagen crosslinks (CTx) and the procollagen type 1 amino-terminal propeptide (PINP) and to determinate vitamin D (25-OHD) levels of elderly Greek women with acute hip fracture. 38 self-sufficient, community-living Greek women with acute hip fracture were included. A similar number of age- and sex-matched controls with no clinically evident fractures were included in the study meeting the same inclusion and exclusion criteria. To exclude the effect of trauma blood samples were drawn within 24 hours from the fracture. Hip fracture group had significantly lower serum 25-OHD levels and significantly higher intact parathormone (PTH) levels compared to the control group but no correlation between PTH and 25-OHD was found in both groups. CTx was significantly correlated with PINP in the total group and in both groups separately but there was no statistical difference of their levels between the two groups. There was high prevalence of severe Vitamin D deficiency within the postmenopausal Greek women with acute hip fracture and the fracture did not influence the above mentioned BTMs. The processes of bone resorption and bone production are in balance during the first 24 hours after the fracture.
Authors and Affiliations
Efstathios Drampalos, Lazaros Oikonomidis, Jeremy Oakley, Ioannis Michos
Keywords
Related Articles
- EP ID EP500474
- DOI 10.22271/ortho.2017.v3.i1i.81
- Views 147
- Downloads 0
Role of flexible elastic nails in diaphyseal fractures of long bones of lower extremities in children of 5-14 years of age
Femoral and tibial fractures are common long-bone injuries in children. Above five years of age all such fractures, when treated conservatively could lead to loss of reduction, malunion, intolerance and complications ass...
Surgical management of unstable supracondylar fractures of humerus in children by closed reduction and percutaneous k wire fixation by crossed versus triple pin configuration: A comparative study
Background: Supracondylar fracture of humerus in children is one of the most common fractures seen in pediatric orthopedic clinic setting worldwide. Closed reduction and percutaneous K wire fixation is preferred method o...
Free flaps in foot and ankle reconstruction: Case series
Introduction: Soft tissue injury around ankle and foot are very difficult to treat. Traditionally in reconstruction of foot and ankle soft tissue defects pedicled flaps have been common mainstay. Evolution in free flap s...
Radiological and clinical evaluation amongst types of tibial tunnel widening and choice of graft fixation implants in ACL reconstruction
Objective: To study incidence of tibial tunnel widening and its functional correlation in patients operated with ACL reconstruction with four fold hamstring tendon autograft. To evaluate radiologically and clinically tun...
Functional outcome of comminuted unstable subtrochanteric fractures treated by proximal femoral nail [PFN]
Background: Subtrochanteric fractures are often difficult to treat and may well be associated with a mortality of more than 20%. The subtrochanteric region is the site of very high mechanical stresses, the medial and pos...