WHETHER COMBINEDLY ADMINISTERED TRANEXAMIC ACID IN TKR IS MORE EFFECTIVE THAN ONLY INTRAVENOUS ADMINISTRATION ?
Journal Title: IJAR-Indian Journal of Applied Research - Year 2018, Vol 8, Issue 3
Abstract
Introduction: The aim of our study is to compare efcacy of 3 doses of intravenous (IV) Tranexamic acid (TXA) versus combined IV and intraarticular TXA in reducing blood loss and transfusion requirement in patients who underwent primary total knee arthroplasty. Methods: Group A patients were administered 3 IV doses of TXA. Group B patients were administered 1 gram of IV and 2 grams of IA dose. Results: The mean 48 hrs drain collection was 238.33 ml in group A and 149 ml in group B. Mean hemoglobin drop is 2.39 gm% in group A and 1.74 gm% in group B. Post operative blood transfusion was required in 12 patients (40%) of group A and 5 patients (16.67%) of group B. Conclusion: IA with IV TXA is more benecial than IV TXA in reducing blood loss in primary total knee arthroplasty.
Authors and Affiliations
Dr. Satyen Joshi, Dr. Brijbhushan Mahajan, Dr. Nitish Agrawal, Dr. Bhalchandra Bhalerao
Keywords
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