White sponge nevus: a case report and literature review
Journal Title: 口腔疾病防治 - Year 2019, Vol 27, Issue 7
Abstract
Objective To explore the etiology, clinical manifestation, diagnosis and treatment of white spongy spot nevus, so as to provide reference for clinical diagnosis and treatment. Methods The clinical data and related literature of a case of white cavernous nevus in oral cavity were retrospectively analyzed. Results White spongy nevus is a rare autosomal dominant hereditary disease with a family history. The mutations of keratin gene K4 and K13 in patients with white spongy nevus are considered to be the main causes. The disease usually starts in children and adolescents and tends to be stable in adulthood. It is characterized by extensive white water-wave folds on the mucosa, soft texture, and affects the bilateral buccal mucosa. Pathological examination usually shows excessive keratosis of epithelial cells, edema and vacuolation in spinous cells, while basal cells are generally normal. In clinic, it should be differentiated from oral leukoplakia, oral lichen planus and oral candidiasis. At present, there is no specific treatment method. Retinoic acid is often applied locally and gargle is used to keep oral hygiene and cleanliness. Patients can not be treated without conscious symptoms. The prognosis of the disease is good and there is no tendency of malignancy. Conclusion White spongy nevus is very rare and easily missed by clinicians. Diagnosis mainly depends on medical history, clinical manifestations and pathological examination. Future research directions should be devoted to finding more effective treatment.
Authors and Affiliations
HONG Pengyu, GAO Jiaxiong, WANG Dianri, TANG Zhangui
Keywords
Related Articles
- EP ID EP622238
- DOI 10.12016/j.issn.2096-1456.2019.07.010
- Views 191
- Downloads 0
Distribution of oral Streptococcus mutans and its correlation with dental caries in children of Bortala Mongolian Autonomous Prefecture
Objective To study the detection rate of Streptococcus mutans in oral cavities of 3-5-year-old Han, Uygur and Mongolian children in Bortala Mongolian Autonomous Prefecture, and the correlation between genotype and dental...
Analysis of the application and effect of the PDCA cycle nursing management model in the treatment of peri-implant mucositis
Objective To explore the application and effect of the PDCA cycle nursing management model in the treatment of peri-implant mucositis.Methods Thirty patients with peri-implant mucositis were treated nonsurgically. Before...
Effect of platelet-rich fibrin extract on the proliferation of gingival fibroblasts
Objective To study the effects of platelet-rich fibrin extract (PRFe) and platelet-derived growth factor (PDGF) released from PRFe on the proliferation of human gingival fibroblasts (HGFs) and to provide an experimental...
Clinical analysis of vitamin B12 deficiency mainly manifested by recurrent aphthous ulcers
Objective To analyze the clinical characteristics and treatment experience of Vitamin B12 (VB12) deficient patients with recurrent aphthous ulcers (RAU) to improve the clinical efficacy. Methods A retrospective analysis...
Application of 3D printing technology in preparation of scaffolds for periodontal tissue regeneration
How to obtain ideal regeneration of periodontal tissue remains a challenge in the clinical treatment of periodontitis. Three-dimensional printing technology is based on computer-aided design, which produces materials wit...