A CASE REPORT OF CARDIOTOXICITY DUE TO HOMEOPATHIC DRUG OVERDOSE
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2014, Vol 3, Issue 4
Abstract
Aconite is one of the most toxic plants. Aconitine and related alkaloids found in the Aconitum species are highly toxic cardiotoxins and neurotoxins. Severe aconite poisoning can occur after accidental ingestion of the wild plant or consumption of an herbal decoction made from aconite roots. The toxic components of Aconitum as aconitine and related alkaloids cause cardiotoxicity, neurotoxicity and gastrointestinal toxicity through their actions on sodium channels. Cardiac manifestations include hypotension and ventricular tachyarrhythmias. Ventricular tachyarrhythmias and refractory cardiovascular collapse, such as in the case of this patient account for lifethreatening toxicities in severe aconite poisoning. In general, vagal slowing is seen in 10 to 20% of fatal intoxications. If higher concentrations are present, supraventricular tachycardia, ventricular tachycardia, torsades de pointes, and other conduction disturbances may be seen. Ventricular fibrillation may be seen, and is often the cause of death. Available clinical evidence suggests that drugs like amiodarone and flecainide are reasonable firstline treatment.
Authors and Affiliations
MilindChandurkar| Professor and Head, Department of Medicine, Rural Medical College of PIMS (DU), Loni, Ahmednagar, Maharashtra, Corresponding author email: drmilindch@gmail.com, Girish Patrike| PG Resident, Department of Medicine, Rural Medical College of PIMS (DU), Loni, Ahmednagar, Maharashtra, NitinChauhan| PG Resident, Department of Medicine, Rural Medical College of PIMS (DU), Loni, Ahmednagar, Maharashtra, SanketMulay| PG Resident, Department of Medicine, Rural Medical College of PIMS (DU), Loni, Ahmednagar, Maharashtra, Manoj Vethekar| PG Resident, Department of Medicine, Rural Medical College of PIMS (DU), Loni, Ahmednagar, Maharashtra, JaweedAkhtar| PG Resident, Department of Medicine, Rural Medical College of PIMS (DU), Loni, Ahmednagar, Maharashtra, Mallikarjun Reddy| PG Resident, Department of Medicine, Rural Medical College of PIMS (DU), Loni, Ahmednagar, Maharashtra
Keywords
Related Articles
- EP ID EP11292
- DOI 10.5958/2319-5886.2014.00057.5
- Views 310
- Downloads 14
HEPATITIS B VIRUS (HBV) AND SYPHILIS CO-INFECTIONS AMONG THE PEOPLE OF EKITI, SOUTH-WEST, NIGERIA
This study was carried out to know the prevalence of hepatitis B, syphilis and co-infection of both among the people of Ekiti, South-West, Nigeria. Individuals and patients who visited the Haematology and Blood Transfu...
Development a Model of the Relationship of Psychological Well-Being with Self-Efficacy, Self-Esteem and Psychological Hardiness in Cancer Patients of Benign Brain Tumors
Brain tumors are common causes of mortality and disabilities in human societies. With the all-round advances in the fields of diagnosis and treatment as a group and team and interdisciplinary is an undeniable necessity....
CASE OF KIKUCHI’ S DISEASE AND SYSTEMIC LUPUS ERYTHEMATOSUS ASSOCIATED WITH ANTIPHOSPHOLIPID ANTIBODY SYNDROME AND COMPLICATED BY HEMOPHAGOCYTIC SYNDROME (HPS)
Kikuchi disease is a rare benign self limited lymphadenopathy. It is often associated with Systemic Lupus Erythematosus which can be diagnosed before; at the same time or after a diagnosis of Kikuchi disease is made. A...
Histopathologic Patterns of Breast Lesions in Northern Saudi Arabia
Objective: The aim of this study was to fnd out the prevalence rates of common types of breast cancer in Northern Saudi Arabia. Methodology: A retrospective cohort study was carried out over a fve-year period in two ref...
Preconcentration and analysis of cannabinoid compounds (THC-9, CBN, CBD) in urine samples by IL-ISFME/D-µ-SPE/HPLC-DAD
In this work we applied a recently developed ionic liquid assisted in-situ solvent formation microextraction coupled with magnetic nano-particle based dispersive micro-solid phase extraction following by HPLC diode arra...