A Cerebellar High-Grade Neuroepithelial Tumour with BCOR Alteration in a five-year-old Child: A case report
Journal Title: Sultan Qaboos University Medical Journal - Year 2019, Vol 19, Issue 2
Abstract
New groups of high-grade neuroepithelial tumours (HGNET) have emerged from the reclassification of central nervous system (CNS) embryonal tumours that have recognised CNS HGNET with BCOR alteration (CNS HGNET-BCOR). We report a two-year, nine-month-old Omani boy who presented to the Royal Hospital, Muscat, Oman, in 2015 with subacute head tilting and neck pain. A well-defined cerebellar lesion was found and he was treated with standard chemoradiotherapy. After a relapse at the age of five years, molecular testing revealed a BCOR alteration. He was treated with further surgery and high-dose chemotherapy; unfortunately, he relapsed and died three years after he was diagnosed.
Authors and Affiliations
Abeer Al-Battashi, Zahra Al Hajri, Arie Perry, Hunaina Al-Kindi, Ibrahim Al-Ghaithi
Keywords
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- EP ID EP49975
- DOI http://dx.doi.org/10.18295/squmj.2019.19.02.012
- Views 345
- Downloads 0
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