A comparative study of pulmonary function tests in different age groups of healthy people and poultry farm workers in Ludhiana city
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2018, Vol 8, Issue 12
Abstract
Background: The air in poultry farms is strongly contaminated with organic, inorganic, and microbial contaminants. Constant exposure to this environment can induce various symptoms and respiratory changes. The most important determinants of lung functions are age. Respiratory muscle strength decreases with age and can impair effective cough, which is important for airway clearance. Pulmonary function tests provide a better understanding of functional changes in the lungs. Aims and Objectives: This study aims to compare the various pulmonary function parameters in various age groups in poultry farm workers and healthy controls. Materials and Methods: Pulmonary function tests were done using computerized autospirometer. The study was carried on 132 subjects (66 each). They were grouped according to their age (18–30 years, >30–40 years, >40–50 years, and >50–60 years). Data were analyzed using Student’s t-test, one-way ANOVA, and post hoc by Bonferroni test. Results: We found that in healthy controls and poultry workers, there was statistically significant (P < 0.05) decrease in forced expiratory volume (FEV)-0.5, FEV1, FEV3, forced expiratory flow (FEF) 50%, FEF 75%, and maximum voluntary ventilation with age. In addition, there was statistically significant (P < 0.05) decrease in FEF 0.2–1.2, peak expiratory flow rate (PEFR), FEF25%, and FEV1/forced vital capacity (FVC) in poultry workers. However, when poultry workers were compared to controls, FVC, FEV0.5, FEV1, FEV3, FEF0.2–1.2, FEF25%, and PEFR were found to be significantly (P < 0.05) decreased. Conclusion: Differences in respiratory pattern in poultry farm workers suggest that poultry dust has additional deteriorating effect on lung functions along with impact of age. Hence, there is a need to increase awareness about harmful effects of poultry dust and the use of personal protective equipment.
Authors and Affiliations
Manpreet Kaur Taluja, Vidushi Gupta, Garima Sharma, Jaspreet Singh Arora
Does Orthosiphon stamineus Benth. enhance GLUT4 translocation in the skeletal muscle of induced type II diabetic rats?
Background: GLUT4 acts as the insulin-responsive glucose transporter, thus promoting the uptake of glucose from circulation into muscle and adipose tissue. Aims and Objectives: The present study was conducted to determin...
Effect of cigarette smoking on erythrocyte sedimentation rate and total leukocyte count
Background: Cigarette smoking is one of the major lifestyle factors which influence the health of human beings. Erythrocyte sedimentation rate (ESR) is a certain biomarker of inflammation. It was a significant predictor...
Efficacy and safety of timolol and latanoprost in the treatment of primary open-angle glaucoma
Background: Glaucoma is a chronic, progressive optic neuropathy which leads to optic nerve damage and loss of visual function. Elevated intraocular pressure (IOP) is the most important and only modifiable risk factor. He...
Evaluation of dipeptidyl peptidase-4 enzyme inhibition by some commonly used gliptins on cutaneous wound healing in albino rats
Background: Dipeptidyl peptidase-4 enzyme not only inhibits incretins but also many other substrates and has wide distribution. Inhibition of this enzyme may have many implications, one of which is to improve wound heali...
Menkes disease - A rare case report
Menkes disease (MD) is a rare, lethal multisystemic disorder of copper metabolism characterized by cerebral and cerebellar neurodegeneration, fair skin with peculiar “kinky hair” and connective tissue abnormalities. It i...