A study of laboratory parameters prothrombin time and 20 minute WBCT in snake bite patients
Journal Title: MedPulse -International Medical Journal - Year 2015, Vol 2, Issue 10
Abstract
Introduction: Since ancient times, snakes have been worshipped, feared and loathed in South Asia. Snake bite is a common occupational hazard of farmers, plantation workers, construction workers, snake charmers and hunters. With urbanization and deforestation, snake bite has become an important public health problem. As the problem is so underrated that, snake bite was finally included in WHO’s list of neglected tropical diseases in early 2009.2 The vast majority of snake bites are accidental in nature. Aims and Objective: To study the various Laboratory Parameters like Prothrombin Time and 20 Minute WBCT In Snake Bite Patients. Methodology: After approval from institutional ethical committee, this Descriptive study carried out at Tertiary care hospital during 2 years (September 2012-September 2014). Total patients were 112. Results: PT was raised in 85 (75.89%) cases and APTT in 77 (68.75%) cases. Out of 85 patients with raised PT, 19 (16.96%) had incoagulable plasma and rest had PT more than 16seconds. Amongst the 77 patients with raised APTT, 19 (16.96%) had incoagulable plasma and remaining had APTT higher than 32seconds but not incoagulable. Patients reaching to hospital between 1 to 6 hours and after more than 6 hours accounted for 67 and 27 respectively, out of them PT was raised in 51 (76.12%) and 24 (88.89%) patients. This was statistically significant. Sensitivity of the20 Minute WBCT test was 50% and specificity was 89.13%. Conclusion: 20 minute whole blood clotting test is having low sensitivity for detecting coagulopathy and should not over-ride clinical assessment based decisions about antivenom administration. More attention should be given to standardize the conditions, timing, use and interpretation of the current 20 WBCT.
Authors and Affiliations
Manisha V Biradar, Rahul Abhange
Keywords
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