Amlodipine: the upcoming threat to Periodontist
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 6
Abstract
Gingival hyperplasia is one of the side effects commonly caused by three major groups of drugs such as a) anticonvulsants b) antihypertensives – calcium channel blockers c) immunosuppressants. Previously among antihypertensives Nifedipine induced enlargements were commonly reported in literature with prevalance rate of 10%. Amlodipine a second generation ca channel blocker was considered as rare drug causing enlargement with a prevalence rate of about only 3.3%.This paper discusses about a 60 yr old male hypertensive patient who received amlodipine at a dose of 5 mg /day remained asymptomatic for 2 yrs later which he reported with massive enlargement of gingiva.
Authors and Affiliations
Sivaranjani, Vineet Kashyap, S. P. K. Kennedy Babu, Ajish Paul K
Keywords
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