Analysis of the Risk of Adverse Drug Reaction on Elderly Patients in General Hospital Surabaya
Journal Title: Indonesian Journal of Clinical Pharmacy - Year 2016, Vol 5, Issue 2
Abstract
Elderly people have the risk of adverse drug reaction (ADR) seven times as high as the adult ones. A research conducted in one of the hospitals in Ireland reported that the incident of ADR was 26%. The objective of this study was to find out the level of ADR risk and types of drugs used to treat elderly inpatients in Dr. Moh. Soewandhi General Hospital Surabaya for the period of November–Desember 2014 utilizing gerontonet score and Screening Tool of Older People’s Prescriptions (STOPP) criteria. The method of this research is cross sectional with a total of 42 participants. In this study, gerontonet score and STOPP criteria was used to analyze the data in order to determine the level of risk and types of drugs. Gerontonet score consists of 6 variables (>4 comorbid, heart failure, liver disorder, amount of drug, history of ADR, and kidney failure); score of ≥4 at presentation identified that the patient is at high risk of ADR. The result of this study showed the variables that mostly determine score was GFR ≤60 mL/min/1,73 m2; 15 participant at high risk of ADR (≥4); and amount of drugs used for treatments; and 9,7% (6/62) kind of drugs used for treatments was included in STOPP criteria: furosemide, aspirin, digoxin, and NSAID (diclofenac, ketoprofen, and meloxicam). The conclusion of this study showed GFR ≤60 mL/min/1,73 m2 and amount of drugs used for treatments increased the risk of ADR.
Authors and Affiliations
Fauna Herawati, Andri Utomo
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