ANTIBIOTIC UTILIZATION STUDY IN PATIENTS WITH NOSOCOMIAL PNEUMONIA IN A PEDIATRIC HOSPITAL IN PACHUCA, HIDALGO
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2016, Vol 7, Issue 6
Abstract
Objective of the study was to identify the antibiotics most frequently used for treatment of nosocomial pneumonia in the DIF Pediatric Hospital of Hidalgo and evaluate the rationality of their prescription by determining the intrinsic value of each antibiotic. This was a descriptive, cross-sectional, indication-prescription study that included patients hospitalized with nosocomial pneumonia from January to December 2014. Data were obtained using the electronic medical record program Histoclin® and were analyzed with SPSS v18. Seventy-six patients stratified by age group were studied with infants predominating in 47.4% of cases. The most frequently used antibiotics were beta-lactams 98.7%, glycopeptides 71%, aminoglycosides 35.5%, imidazole derivatives 32.9% and lincosamides 22.4%. Antibiotic treatment interruption at 48–72 hours was 12% (meropenem, cefepime and vancomycin). Intrinsic value according to blood cultures was correct in 100% of cases. Total consumption of antibiotics expressed as DDD/100 bed-days was for imipenem 9.23 DDD/100 bed-days, amphotericin B 9 DDD/100 bed-days, cefepime 8.27 DDD/100 bed-days, and vancomycin 8.11 DDD/100 bed-days. Total consumption of antibiotics during this period was 2,740,019.85 mg with a total investment of $2,724, 224.30 pesos. The intrinsic value of the evaluated drugs was correct. We recommend a standardized antibiotic administration guideline that favors their rational use.
Authors and Affiliations
Lourdes Cristina Carrillo-Alarcón , David Chávez- Gallegos , Érika Moedano- Álvarez , Moisés Ocampo- Torres , Lizbeth Norato- Canales , Marco A. Escamilla- Acosta
Keywords
Related Articles
- EP ID EP123337
- DOI 10.7897/2230-8407.07657
- Views 127
- Downloads 0
PHYTOCHEMISTRY AND BIOINFORMATICS APPROACH FOR THE EVALUATION OF MEDICINAL PROPERTIES OF THE HERB, EXACUM BICOLOR ROXB.
Exacum bicolor Roxb. (Gentianaceae) is a phytochemically unexplored traditional medicinal herb, generally distributed in the grasslands of northern Kerala during July-October. The present study through GC-MS analysis rev...
A CLINICAL STUDY TO EVALUATE THE EFFICACY OF JALAUKAVACHARANA AND SARIVADYASAVA IN YUVANAPIDAKA (ACNE VULGARIS)
Yuvana pidaka is a disease produced due to morbid Kapha, Vata and Rakta Dosha involving Rasavaha and Raktavaha Srotas. This disease under the heading of Kshudra roga and later scholars of the science accepted the same,...
STUDY OF ANTIULCER ACTIVITY OF ROOTS OF ALANGIUM SALVIFOLIUM LINN. IN PYLORUS LIGATED RATS
Different extracts of Alangium salvifolium Linn. roots were tested for its antiulcer activity in aspirin induced and pylorus ligated rats model. The effect was assessed by parameters like Total acidity(TA),Free acidity(F...
ANTI-DIABETIC EFFECT OF MORUS ALBA ON RABBIT AS ANIMAL MODEL
A study of ancient literature indicates that diabetes was fairly well known and well conceived as an entity in India. The nature has provided abundant plant wealth for all the living creatures, which possess medicinal vi...
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF FAROPENEM IN BULK AND PHARMACEUTICAL FORMULATION USING THE RP-HPLC METHOD
A simple, specific and accurate reverse phase high performance liquid chromatographic method was developed for the determination Faropenem in Bulk and pharmaceutical dosage form. The column used was Symmetry C18 (4.6 x...