ANTICANCER ACTIVITY OF ZINC OXIDE AND ZINC OXIDE/CADMIUM SULFIDE NANOCOMPOSITES
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2019, Vol 12, Issue 2
Abstract
Objective: The objective of this study is to investigate the anticancer activity of zinc oxide (ZnO) and ZnO/cadmium sulfide (CdS) nanoparticles (NPs). These NPs were active index against five human tumor cell lines, namely hepatocellular carcinoma, mammary gland (MCF-7), epidermoid carcinoma (HEP2), colorectal carcinoma (HCT-116), and rhabdomyosarcoma (RD). Methods: ZnO and ZnO/CdS NPs were synthesized using zinc acetate dihydrate and oxalic acid. The samples are characterized by Fourier-transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, energy-dispersive X-ray spectroscopy, and atomic force microscopy (AFM). Results: The results were indicated that these NPs can be used to made drug delivery system depending on ZnO and ZnO/CdS nanocomposites for its potential role in enhancing the anticancer efficacy of doxorubicin as well as work on reducing side effects. Conclusions: ZnO and ZnO/CdS nanocomposites can be used anticancer for five human tumor cells.
Authors and Affiliations
ALI JABBAR JASIM MAKKAWI, NOOR HADI AYSA, FATTIMA-ALZAHRA G GASSIM
Keywords
Related Articles
- EP ID EP608826
- DOI -
- Views 119
- Downloads 0
RAPID SEPARATION AND DETERMINATION OF RIZATRIPTAN N-OXIDE IMPURITY IN RIZATRIPTAN BENZOATE IN A BULK DRUG SUBSTANCE BY REVERSE PHASE LIQUID CHROMATOGRAPHY
Objective: The objective is described to develop and validate a simple, reliable, precise, and specific analytical method for rapid separation and determination of N-oxide impurity in rizatriptan Benzoate active pharmace...
ANTIBACTERIAL ACTIVITY OF ANNONA SQUAMOSA L. AND ANNONA RETICULATA L. AGAINST CLINICAL ISOLATES OF MUTANS STREPTOCOCCI THE CAUSATIVE AGENTS OF DENTAL CARIES
ABSTRACTObjective: Evaluation of antibacterial activity of Annona squamosa L and Annona reticulata L against Streptococcus mutans and Streptococcus sobrinus(mutans streptococci MS) the causative agent of dental caries.Me...
EFFECTIVENESS OF LOW-COST CUSTOMIZED SADDLE PILLOW ON PAIN IN POST-EPISIOTOMY PATIENTS
Objective: To examine the effectiveness of customized saddle pillow for pain in post-episiotomy patients and also to analyze the duration of sitting for breastfeeding and other functional activities following episiotomy....
EFFECT OF PRE EXAMINATION STRESS ON OLFACTORY SENSITIVITY IN COLLEGE STUDENTS.
 Objective: The present study was undertaken to assess the effect of pre-examination stress on olfactory sensitivity in college students.Methods: A total of 80 apparently healthy males and females were included in the s...
SYNTHESIS OF SOME NOVEL PERYLENE DI IMIDES AND EVALUATION OF THEIR ANTI CANCER ACTIVITY
Objective: The main objective of the study is to synthesis some novel perylene di imides and to evaluate for anti oxidant activity and anticancer activity.Methods: Antioxidant assay was carried on to study the reducing a...