Antifungal Drugs Loaded Nanosponges to Improve Bioavailability of Antifungal Drugs; A Review

Journal Title: Open Access Journal of Pharmaceutical Research - Year 2021, Vol 5, Issue 4

Abstract

Fungal infections have become a major concern in this era for human health leading to morbidity and mortality. A lot of antifungal agents are available for treatment, with poor therapeutic outcomes due to poor bioavailability, toxicity, and resistance challenges. Ordinary dosage forms are unable to meet the clinical needs. Nanosponges provide a promising drug delivery system overcoming major challenges concerned with antifungal agents. Nanosponges improves solubility, permeation, taste masking and stability of antifungal agents. It serves as an important tool for providing controlled release dosage forms. The nanosponges are easier to formulate and convenient for bilk manufacturing. Nanosponges thus provide various benefits to clinician to cope the overcoming demand of fungal infectious disease.

Authors and Affiliations

Qaiser M, Shahzad Q*, Hamza M and Hussain S

Keywords

Related Articles

Pharmacological Action of Taxifolin: A Review

Taxifolin is a potent plant flavonoid. The most sources of taxifolin include onions, tamarind seeds, French maritime bark and milk thistle and are also commercially available in semisynthetic forms. It was within the mi...

Exploring the Interplay of Socio-Demographic Factors, Medication Preferences, and Adherence Behaviors in Candidiasis Treatment Outcomes in Ghanaian Females

Introduction: Candidiasis, a fungal infection caused primarily by Candida species, affects millions of people worldwide, particularly women. Despite the availability of antifungal treatments, treatment failures remain a...

Detection of False Medication Adherence

The lack of adherence to treatment is considered in general, to be higher than 50%. Given the magnitude of the problem, it is sought to detect it and solve it through various methods — of which, there are few studies an...

Comprehensive Review of Phytochemistry and Bioactivities of Citrullus Colocynthis (L.) Schrad

Citrullus colocynthis is a restorative plant which has been used in traditional medicinal systems. Extracts in different solvents are found to possess antibacterial, antifungal, antioxidant, analgesic, hypoglycemic, hyp...

Insights into the Effect of Trehalose and Cyclodextrin Molecules on Dissolution Characteristics of Furosemide Lyophilised Powder

The aim of this work is to enhance the dissolution of furosemide, a hydrophobic drug used in treating hypertension. Solid dispersion via lyophilisation was employed for this purpose. Sugar and oligosaccharide, trehalose...

Download PDF file
  • EP ID EP748597
  • DOI 10.23880/oajpr-16000255
  • Views 64
  • Downloads 0

How To Cite

Qaiser M, Shahzad Q*, Hamza M and Hussain S (2021). Antifungal Drugs Loaded Nanosponges to Improve Bioavailability of Antifungal Drugs; A Review. Open Access Journal of Pharmaceutical Research, 5(4), -. https://www.europub.co.uk/articles/-A-748597