Bupivacaine 0.125% versus bupivacaine 0.125% with different doses of fentanyl for epidural labour analgesia: A randomised double blind study

Journal Title: International Journal of Medical Science and Public Health - Year 2014, Vol 3, Issue 4

Abstract

Background: Epidural analgesia is the most commonly used method for labour analgesia . Aims & Objective: To evaluate the safe dose of fentanyl added to Bupivacaine 0.125% and its effect on quality and duration of analgesia with side - effects. Materials and Methods: Forty - five healthy nulliparous women, ASA physical status I and II with an uncomplicated pregnancy and single fetus in vertex position were given lumbar epidural analgesi a. Patients in Group A (n=15) received Bupivacaine 0.125 percent; Group B (n=15) and C (n=15) received the same agents as Group A but with addition to the initial dose of 2 mcg/ml or 4 mcg/ml of fentanyl respectively. All the patients were evaluated for du ration and quality of analgesia, duration of labour, method of delivery and side effects . Results: Addition of either 2 mcg/ml or 4mcg/ml of fentanyl resulted in longer duration of analgesia (132.2 ± 12.4 min ute s and 188.20 ± 18.5 min ute s respectively versus 92.5 ± 10.2 min ute s) and also decreased number of top up doses significantly. Quality of analgesia was better in Group B and Group C as compared to Group A. Addition of fentanyl did not affect the duration of labour, the method of delivery and fetal outcome. Conclusion: Combination of Fentanyl 2 mcg/ml and Fentanyl 4 mcg/ml with Bupivacaine 0.125% is both and safe for providing labour analgesia via epidural route.

Authors and Affiliations

Dhara Patel, Prerana Mankad, Sahil Banshal, Jayendra Makwana, Shakuntala Goswami, Bharat Shah

Keywords

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  • EP ID EP100812
  • DOI DOI: 10.5455/ijm sph. 2014. 23 0120141
  • Views 167
  • Downloads 0

How To Cite

Dhara Patel, Prerana Mankad, Sahil Banshal, Jayendra Makwana, Shakuntala Goswami, Bharat Shah (2014). Bupivacaine 0.125% versus bupivacaine 0.125% with different doses of fentanyl for epidural labour analgesia: A randomised double blind study. International Journal of Medical Science and Public Health, 3(4), 418-421. https://www.europub.co.uk/articles/-A-100812