Color Doppler Study of Endometrial Spiral Artery in Unexplained Infertility
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 4
Abstract
Infertility, defined as failure to conceive within one year despite normal cohabitation (Zabek 1996; Barbieri 1996) or within two years according to the European Society for Human Reproduction and Embryology (Forti and Krausz 1998), presents in 10-15% of all couples. Typically, 80% of couples (aged 18-28 years) will conceive over a one-year period and another 10% conceive during the following year. The rate of infertility has slowly been increasing (Stephen and Chandra 1998; Silverberg 2000). The prevalence of unexplained infertility is about 15-30% and diagnosis of unexplained infertility is made only after exclusion of other causes of infertility.[1] Unexplained infertility may reflect a diminished ovarian reserve, a disorder of oogenesis or suboptimal endometrial receptivity. There are so many test available that may reveal ovarian dysfunction and endometrium is assessed by its thickness and describing its appearance.[2] Blood flow to endometrium come from radial artery which divides before the myo-endometrial junction to form basal artery that supply portion of endometrium and the spiral artery that supply the endometrial surface.[3] In fertile women uterine spiral artery perfusion has been found to improve during the luteal phase which coincide with the implantation window, endometrial receptivity is regulated by many factors which include uterine perfusion.[4] Doppler ultrasonography is an important tool and a non invasive procedure to assess uterine perfusion. So the aim of this study is to evaluate the mid luteal phase endometrial spiral artery blood flow in unexplained infertility patient and compare the parameters with fertile control in order to reveal the possible role of uterine artery perfusion in etiopathogenesis of unexplained infertility.
Authors and Affiliations
Dr. Shivani Singh
Keywords
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