Comparison of the Hemodynamic Effects of Intravenous Induction with Thiopentone Sodium, Protocol and Etomidate in Patients Undergoing General Anesthesia
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 8
Abstract
AIM:To compare the haemodynamic effectsof thiopentone,propofol and etomidate and to study the side effects.MATERIALS AND METHODS:After taking institutional ethical committee approval and informed consent ,90 patients aged between 20-50 yrs of ASA Grade 1&11 undergoing elective surgeries under general anaesthesia were randomly divided into3groups Group T, Group P and Group E.Group Tpatients were induced with thiopental 5mg/kg, Group P – patients received propofol 2mg/kg and Group E received etomidate 0.3mg/kg. Haemodynamic variables like H.R,B.P(systolic and diastolic) and Spo2 recorded before induction and at 1,3.5,10.15 and 30 mts post induction and S.E if any are noted.RESULTS :There was significant fall in HR in propofol group compared to thiopentone and etomidate groups. There was also significant decrease in systolic blood pressure , diastolic blood pressure and mean blood pressure in patients of propofol and thiopentone groups than those of etomidate groups. Conclusion: Present study concludes that etomidate is an effective induction agent with good cardiovascular stability when compared with thiopentone and propofol.
Authors and Affiliations
Dr. A. Usha Rani, Dr. M. Santhi Sree
Keywords
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- EP ID EP381398
- DOI 10.9790/0853-1708104146.
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