Current status and challenge of biomarker studies for progressive diabetic kidney disease
Journal Title: Biomedical Transformation - Year 2021, Vol 2, Issue 1
Abstract
Diabetic kidney disease (DKD) is the main cause of end stage renal disease and death in patients with diabetic mellitus (DM) . Prognostic assessment for patients with DKD is critical to reduce the risk of disease progression and incidence of complications or deaths. This review mainly discussed the current research status of biomarkers which might predict the progression of DKD, including the commonly used albuminuria and glomerular filtration rate (GFR) , as well as novel biomarkers like tumor necrosis factor receptor (TNFR) and renal tubular markers. Meanwhile, we discussed the potential challenges in the development and application of these biomarkers in progressive DKD.
Authors and Affiliations
Feng Songtao, Liu Bicheng
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