Dexmedetomidine as an Adjunct to Spinal Anesthesia in Urological Procedures
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 1
Abstract
Introduction: Patients undergoing urological procedures under spinal anaesthesia are usually elderly having comorbid conditions. Dexmedetomidine, the new highly selective α-2 agonists is being used as an adjuvant in spinal anaesthesia with improved quality of anaesthesia and analgesia and minimal side effects. The present study was designed to evaluate the effect of intrathecal dexmedetomidine to bupivacaine in spinal anesthesia for urological procedures. Material and Methods: Sixty patients of ASA class I and II were randomly divided into two groups of thirty patients each. The control group received hyperbaric bupivacaine 15 mg + 0.5 ml normal saline (3.5 ml).The study group received hyperbaric bupivacaine 15 mg +10 mcg dexmedetomidine diluted in 0.5 ml normal saline (3.5ml). Results: The time taken to reach the highest sensory level was 8.5 ± 0.5 minutes in control group while 6.2 ± 0.4 minutes in study group. The mean time to reach the bromage 3 was 10.1 ± 2.9 minutes in control group while 7.8 ± 1.9 minutes in study group. Time taken to sensory regression to S1 and duration of motor blockade was significantly higher (311 ± 36.6 min and 286 ± 34.2 min) in study group when compared to control group (230 ± 19.3 min and 197.9 ± 17.5 min). The duration of analgesia was significantly higher (339.7 ± 47.4 min) in study group as compared to control group (272.1 ± 39 min) Conclusion: Addition of dexmeditomidine to hyperbaric bupivacaine in spinal anaesthesia results in early onset of sensory and motor block, prolongs duration of motor and sensory block, improves quality of intraoperative and post operative analgesia with good hemodynamic stability and minimal side effects.
Authors and Affiliations
Mehmooda Akhter, Abdul Waheed Mir, Bilal Ahmad, Faroz Ahmad, Suhail Sidiq, Mohamad Akbar Shah, Sofi Khalid
Keywords
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