Different Uses of Chitosan for Treating Serious Obstetric Hemorrhages
Journal Title: Gynecology and Obstetrics Research – Open Journal - Year 2017, Vol 3, Issue 1
Abstract
Postpartum hemorrhage is a major cause of maternal death worldwide. Many therapeutic strategies have been developed to reduce maternal morbidity and mortality like oxytocin, prostaglandin, and uterine balloons. A new member of the therapeutic arsenal has recently emerged, the chitosan (Celox®), used since several years by military doctors to stop bleeding of combat wounds. In 2012, a first study was reported with the successful use of chitosan-coated gauze to treat severe postpartum hemorrhage. We report here three cases of the use of chitosan to treat life-threatening obstetric bleeding. In the first case, a pelvic packing with chitosan gauze after hemostatic hysterectomy with persistent bleeding. In the second case, the use of chitosan powder in a case of severe bleeding from multiple vaginal tears. In the third case, the use of chitosan gauze in uterine packing for postpartum hemorrhage by atonia. Postpartum hemorrhage of uterine origin resistant to treatment with prostaglandins can be treated with chitosancoated gauze. This treatment requires no training and its costs are one fifth those of a Bakri® intrauterine balloon. Using these two forms of chitosan, powder and gauze, we have developed a new therapeutic method at our disposal for dealing with the most serious cases of bleeding.
Authors and Affiliations
Gabriel Carles
Keywords
Related Articles
- EP ID EP553794
- DOI 10.17140/GOROJ-3-129
- Views 179
- Downloads 0
The Identification of Pregnant Women at Risk for Child Abuse: Methodology
Background: The prevention of child abuse should starts as early as possible in the life of children living in families at risk for abuse. We describe a two-stage selection procedure to identify those pregnant women who...
Case Report of Unusual Stromal Luteinization in High-Grade Papillary Serous Carcinoma of the Ovary
Stromal luteinization has been reported to be associated with benign and malignant epithelial ovarian tumors, predominantly mucinous and often endometrioid ovarian neoplasm. We report here an unusual case of marked ovari...
High-Throughput Next Generation Sequencing: Applications in Reproductive Diagnosis and Research
The genetic information contained within a cell is transferred through the process of transcription of genes within a genome to produce messenger RNAs (mRNAs) and translation of mRNAs to synthesize proteins. The central...
Pelvic Actinomycosis Masquerading as Malignancy
Pelvic actinomycosis is a chronic granulomatous suppurative disease caused by Actinomyces israeli. The opportunistic anaerobic bacterium Actinomycosis israeli is a normal part of the human flora in the oropharynx, gastro...
Developmental Exposure to Endocrine Disrupting Chemicals Alters the Epigenome: Identification of Reprogrammed Targets
Endocrine disruptions induced by environmental toxicants have placed an immense burden on society to properly diagnose, treat and attempt to alleviate symptoms and disease. Environmental exposures during critical periods...