Evaluation Antioxidant and Antibacterial Activities of n-Butanol Fraction of Conocarpus Erectus L. Leaves Extract
Journal Title: International Journal of Pharmaceutical and Medicinal Reserach - Year 2016, Vol 4, Issue 6
Abstract
N-butanol extract of Conocarpus erectus L. leaves was studied for antioxidant and antibacterial activities. In vitro systems for example, 1, 1- diphenyl-2 picrylhydrazyl (DPPH) radical, and antioxidant capacity (Ferric Reducing Antioxidant Power, FRAP assay). The antibacterial activity was determined using the hole-in-plate agar diffusion. The extract scavenged DPPH radicals comparable with ascorbic acid and butyl hydroxytoluene (BHT). The n-butanol extract of Conocarpus erectus L. leaves showed high free radical scavenging activity toward DPPH radical between (29.87-79.33). The n-butanol extract had radical scavenging activity less than the Ascorbic acid (34.61-80.76) and butyl hydroxytoluene (BHT) (33.33-66.66). The results indicated the antioxidant capacity of butanol extract had a significantly (0.50-1.11nm) much higher than ascorbic acid (0.5-0.86nm ) and butyl hydroxytoluene (BHT) (0.30-0.76nm). Antibacterial activity was found to be present in nbutanol extract of Conocarpus erectus L. leaves being highest in Straptococcus (22mm). Zones of inhibition for E.coli, Staph. aureus and Enterobacter were 21, 20 and 19 respectively. Results show plants to possess antibacterial activity.
Authors and Affiliations
Rawa A. Hussein
Keywords
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