Evaluation of Intracranial Ring Lesions by Diffusion-Weighted Imaging and in Vivo Proton Magnetic Resonance Spectroscopy
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 11
Abstract
AIMS & OBJECTIVES: To assess the combined role of diffusion weighted imaging and spectroscopy in differentiating ring enhancing intracranial cystic lesions. MATERIALS AND METHIODS: The study was conducted from Oct 2011 to Sep 2013. Thirty (30) patients having ring enhancing intracranial cystic lesions were included in the study. 1.5 tesla MRI ACHEIVA (Phillips) with routine MRI sequences with diffusion weighted imaging (DWI) and ADC mapping followed by ADC value in the center of lesion was used. Proton Magnetic resonance spectroscopy was performed on these patients followed by T1W contrast. The radiological diagnosis was correlated with histopathological examination in 12 patients and the remaining were evaluated clinical parameters and blood tests by the clinicians. RESULTS: Infective lesions were characterized by decreased Ch/NAA and decreased/ near normal Ch/Cr ratio as compared to ring enhancing cystic neoplastic lesions. Elevated lactate and lipid peaks were found to be characteristic for Tuberculomas. Cystic neoplastic lesions could be differentiated from infective lesions. Cerebral abscesses differed on the basis of elevated lactate and amino acid peaks. Brain abscesses showed high signal intensity in DWI and reduced ADC in the centre of lesion as compared to cystic neoplastic lesions. CONCLUSIONS: The combined role of MRI with MRS and Difusion weighted imaging is found to be useful in accurate evaluation and differentiation of intra cranial cystic ring enhancing lesions. Reduced ADC value with diffusion restriction is highly suggestive of brain abscess while in absence of restriction; magnetic resonance spectroscopy is useful in distinguishing abscess from other infective lesions and cystic neoplasms
Authors and Affiliations
Samita Singal
Keywords
Related Articles
- EP ID EP214805
- DOI -
- Views 77
- Downloads 0
A Study to Assess the Knowledge Regarding Nosocomial Infection among B.Sc. Nursing Students in Selected Nursing Institutions of Pune City
Nosocomial infection or Hospital acquired infection (HAI) are frequent, complication affecting hospitalized patients after the admission within 72 hours. Now a days students are taking clinical experience from various he...
The Prevalence of Thyroid Dysfunction and Thyroid Autoantibodies Among Type 2 diabetic Patients in Nnewi, South Eastern Nigeria
Background: This study was carried out to determine the prevalence of anti-thyroid antibodies and Thyroid dysfunction (TD) among Type 2 Diabetic (T2DM) patients in our environment. Methods: The study comprises one hundre...
Role of VIA and Pap smear of cervix as screening in low resource setting
Aim of the study: to compare Visual inspection with acetic acid and pap smear for cervical cancer screening in low resource setting. Materials and Method: Random women age ranging from 20-70 years were subjected to per s...
To Compare the Efficacy of Conservative Management with Surgery for Treatment of Chronic Low Back Pain: A Randomised Prospective Cohort Study
Background: Low back pain is a common medical problem in general population with high morbidity and healthcare costs. The optimal management strategy, including the role of surgical intervention, remains controversial. W...
Vitamin D Status and Glycemic Control in Type 2 Diabetes Mellitus
India has widespread prevalence of diabetes and hypovitaminosis D. This study was conducted to evaluate the relationship between serum 25-hydroxyvitamin D [25(OH)D] and glycemic control in patients with type 2 Diabetes M...