Formulation and evaluation of modified drug release tablet in tablet dosage with novel coating of β2-adrenergic receptor agonists
Journal Title: International Journal of Pharmacology and Clinical Research (IJPCR) - Year 2018, Vol 2, Issue 1
Abstract
Controlled drug dosage forms offer many advantages, such as nearly constant drug level at the site of action, prevention of peak-valley fluctuation, reduction in dose of drug, reduced dosage frequency, avoidance of side effects and improved patient compliance. Hence an attempt has been made to develop modified drug release by using tablet in tablet technique with barrier coating by using natural and synthetic polymers with Salbutamol as model drug. The inner core tablets were prepared by using direct compression method. The formulation F7 was selected for press coat by using different polymers like HPMC, Ethyl cellulose, Xanthum gum and Guar gum in different ratios among which 1part of Xanthum gum and 1part of Guar gum was optimized based on the lag time (20.75% in 4 hours) and percent of drug release and also further evaluated.
Authors and Affiliations
Srikanth Choudary Pallothu
Keywords
Related Articles
- EP ID EP540592
- DOI -
- Views 131
- Downloads 0
Phytochemical screening and in vitro antioxidant activity of extracts of jasminum sessiliflorum
Objectives The aims of this research were to carry out the preliminary phytochemical screening and antioxidant activity of different extracts of J. sessiliflorum. The different anti-oxidant methods carried out were DPPH...
Invitro alpha amylase effect of Sida acuta Burm
Introduction Sida acuta is shrub indigenous to pantropical areas, widely distributed in regions and found in pastures, waste lands, cultivated lands, roadsides, lawns and planted forests. Sida acuta is ethanomedically us...
Geriatric nutrition- nutrition for optimal health, energy, and longevity in old age people
The over-sixties make up the fastest growing segment of the population in most countries. Although life expectancy has also increased dramatically over the last 100 years, this segment of the population is susceptible to...
Preliminary study of Prescription audit for evaluation of prescribing pattern of the doctors for rational drug therapy in a newly developing Pandit Jawaharlal Nehru Govt. Medical College and Hospital Chamba –HP (Pt. JLNGMCH – Chamba- HP)
Prescription audit is necessary to know the art of prescription practices to improve rational pharmacotherapy. Present study is an observational study and was undertaken from August 2018 to October 2018 for which data wa...
Liquimega Liquicaps; an effective supplementation for everybody, for everyday, for life
Omega-3,6,9 fatty acids are considered as essential fatty acids. They are necessary for human health but the body can't make them. Research shows that omega-3,6,9 fatty acids reduce inflammation and may help lower risk o...