Granular Ameloblastoma of Jaw: A Rare Histopathological Entity
Journal Title: National Journal of Laboratory Medicine - Year 2016, Vol 5, Issue 3
Abstract
Ameloblastoma is a benign odontogenic tumor of epithelial origin. Granular ameloblastoma is a rare subtype of ameloblastoma. In most of the cases, it is found admixed with other patterns of ameloblastoma. Pathogenesis of granular change in tumor cells seems to be age-related; however, ultrastructural and immunohistochemical studies showed that cytoplasmic granularity is caused by lysosomal overload. We report a case of granular ameloblastoma in mandible of a 45-year-old male. The unique microscopic features of granular ameloblastoma help in differential diagnosis from other odontogenic and non odontogenic tumors with granular cell component. Radical excision with adequate margin of uninvolved tissue is important as it has a high recurrence rate.
Authors and Affiliations
Dr. Prachi Nayak, Dr. Sachin Jain, Dr. Sphurti Srivastava, Dr. Premala Anthony Singh, Dr. Kinshuk Chatterjee
Keywords
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- EP ID EP381254
- DOI 10.7860/NJLM/2016/19600:2142
- Views 108
- Downloads 0
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