Hepatit C veya interferon tedavisi ile ilişkili tiroit hastalıkları
Journal Title: Journal of Microbiology and Infectious Diseases - Year 2013, Vol 3, Issue 3
Abstract
Karaciğer dışı birçok hastalık kronik hepatit C virüs (HCV) enfeksiyonu (hematolojik hastalıklar, böbrek hastalığı, dermatolojik problemler) ile ilişkilendirilmiştir. HCV enfeksiyonunun klinik ya da subklinik oto-immün tiroid hastalıklarının artmış insidansıyla da ilişkili olduğu gösterilmiştir. Ayrıca, kronik HCV enfeksiyonunun interferon (IFN)-α ile tedavisi vakaların % 40’ına kadar olan kısmında subklinik veya klinik tiroidit ile ilişkilidir. İnterferon ilişkili tiroidit (İİT), otoimmün tip ve otoimmün olmayan tip olarak sınıflandırılabilir. Mevcut çalışmalar viral yük, viral genotip ve tedavi rejiminin kronik hepatit C hastalarında İİT gelişimini etkilemediğini, ayrıca İİT gelişmesinin kalıcı viral yanıt (KVY) için bir gösterge olmadığını, ancak, genetik faktörler, cinsiyet, HCV enfeksiyonu ve tiroid antikor (TAb) pozitifliğinin rol oynayabileceğini göstermektedir. Anahtar kelimeler: Hepatit C, interferon, tiroid hastalıkları
Authors and Affiliations
Şener Barut, Özgür Günal
Keywords
Related Articles
- EP ID EP93517
- DOI 10.5799/ahinjs.02.2013.03.0099
- Views 196
- Downloads 0
Is it really an erysipelas?
Primary cutaneous anaplastic large cell lymphoma is characterized by red-brown plaques or nodules on the skin, may mimic skin and soft tissue infections and is usually related with high mortality. A case that was follow...
A Case of Meropenem Induced Cholestasis
Meropenem is a broad-spectrum carbapenem antibiotic used for complicated hospital infections. Mild aminotransferase elevations have been reported in meropenem recipients, but cholestasis is rare. A 70 year old man was ad...
Feco-orally transmitted viral hepatitis in a tertiary care hospital in urban India
Objective: To investigate the magnitude and pattern of hepatitis viral markers in feco-orally transmitted acute viral hepatitis with their relation to age and sex. Methods: This prospective study was carried out in two...
Apophysomyces elegans Caused Rhino-Orbito Mucormycosis: An Emerging Infection in Immunocompetent Individuals
Mucormycosis is a rare necrotizing angioinvasive infection caused by fungi of the class Zygomycetes (order Mucorales). It predominantly occurs in immunocompromised/ predisposed individuals. Recent surge in its incidence...
Results of Entecavir treatment in patients with chronic hepatitis B
Objective: This study was designed to determine the efficacy and safety of Entecavir (ETV) after 96 weeks treatment in patients with chronic viral hepatitis B (CHB). Methods: Thirty-eight patients were included into the...