Histopathological study of lesions of nose, paranasal sinuses and nasopharynx at tertiary care centre
Journal Title: Medpulse International Journal of Pathology - Year 2018, Vol 6, Issue 2
Abstract
Background: A variety of non-neoplastic and neoplastic conditions involving the nasal cavity, paranasal sinuses (PNS), and nasopharynx are commonly encountered in clinical practice. Due to anatomical proximity of these diseases to central nervous system and other vital organs, accurate assessment of pathological specimen play a major role in assisting clinician to achieve an optimal management of patients with the diseases. Aims and Objective: (1) To study the incidence of benign and malignant lesions of nose and paranasal sinuses (PNS). (2) To study various lesions in reference to sex differences and symptomatology. (3) To compare findings of the study with other authors. Materials and Methods: Present study was conducted for a period of 2 years from January 2016 to December 2017. Total 62 cases were studied for histopathological examination. Clinico pathological and radiological correlation also carried out. Routine gross examination and required number of sections were taken and stained with hematoxylin and eosin. Results: The Age ranges from 10 to 69 years. In present study nasal masses are more common in male than female. Out of 62 cases 42 (67%) were male compare to 18 (33%) female. Non neoplastic lesions are more common than neoplastic lesion. Out of 62 cases, 50 cases were Non-neoplastic (80%) and 12 (20%) cases were neoplastic. Inflammatory nasal polyp is most common non neoplastic lesion whereas inverted papilloma is most common benign neoplastic lesion and most common malignant mass were Nasopharyngeal carcinoma. Conclusion: Sinonasal masses have various differential diagnoses. The presenting feature of the neoplastic and the non- neoplastic sinonasal masses may be clinically indistinguishable from each other. Malignant masses should be distinguished from the other types. A careful histopathological examination is necessary to decide the nature of any particular lesion.
Authors and Affiliations
Asha Satvara, Yogendra Madan, Alaknanda Atara, Shamim S Sheikh, P M Santwani
Keywords
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Background: A variety of non-neoplastic and neoplastic conditions involving the nasal cavity, paranasal sinuses (PNS), and nasopharynx are commonly encountered in clinical practice. Due to anatomical proximity of these d...