HYPONATREMIA & WATER INTOXICATION WITH CARBAMAZEPINE: A RARE CASE REPORT.
Journal Title: International Journal Of Medical Case Reports - Year 2016, Vol 2, Issue 2
Abstract
Many of the patients undergoing psychiatric treatment suffer from polydipsia and polyuria. In most of the instances there is no medically identifiable cause of this polydipsia and polyuria1. Dilutional hyponatremia is one of the common complication of such polydipsia and if not recognized in time may lead to water intoxication and further complications. Here we present a rather rare case of 50 years male who was a diagnosed case of schizoaffective disorder on carbamazepine & qutiapine. He developed hyponatremia and progressed to water intoxication.The cause of the hyponatremia in this patient was Syndrome of inappropriate antidiuretic hormone (SIADH) secondary to of carbamazepine (CBZ) therapy2. CBZ has antidiuretic properties3 which was responsible for water intoxication and dilutional hyponatremia in this patient. The patient was investigated and was found to be having serum sodium level of 130mmol/lit. Patient was treated by fluid restriction and discontinuation of carbamazepine (4,5,6).
Authors and Affiliations
javed ather Siddiqui, Shazia Farheen Qureshi, Mahmoud Amairi, Abdullah Al-Zahrani
Keywords
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