Hypoparathyroidism In Dialysis Patients of Bagalkot
Journal Title: International Journal of Medical and Health Sciences - Year 2012, Vol 1, Issue 3
Abstract
Introduction: Chronic kidney disease (CKD) is associated with a variety of bone disorders and abnormality of “Calcium” and “Phosphate” metabolism. Chronic kidney disease associated mineral bone disorder (CKDMBD) is an area of ongoing discussion because of its role in morbidity and mortality in dialysis patients. Both Indian and international data, regarding parathyroid levels in chronic kidney disease patients highlight predominant hyperparathyroidism in dialysis patients and very few as hypo parathyriodism.We undertook this study to determine the prevalence of hypo and hyper-parathyroid state in our dialysis patients and for better understanding and management of CKD-MBD . Materials & Methods: 40 adult patients (> 18 years age) who met the inclusion criteria and were on hemodialysis in SNMC and HSK HOSPITAL AND RESEARCH CENTER and end stage renal disease (ESRD) (glomerular filtration rate <15 ml/kg/m2) patients attending nephrology clinics were enrolled in the study. Patients’ parathyroid status was defined as per target recommendation of Kidney foundation disease outcomes quality initiatives [KDOQI] – hypo parathyroid when, intact parathyroid (iPTH) < 150 pg/ ml as group (A) , hyper parathyroid, iPTH > 300pg/ml as group (B) and patients with values between 150pg/ml-300pg/ml to group(C) as per standard protocol. Results and conclusion: A total of 40patients all (100%) were on hemodialysis. Mean age of these patients was 51.3 ± 5.3years.30 (75%) were males and18 (45%) were diabetics. Mean duration on dialysis was 15.77±8.8 months. Twenty out of 32 patients (50%) had hypoparathyroidism, 12(30%) hyperparathyroidism and remaining 8(20%) were in normal ranges.Hypoparathyroidism is more common (50%) in our dialysis patients as compared to hyperparathyroidism (30%).
Authors and Affiliations
Pramiladevi. R, Kora Shreeram, Khanapure Shashidhar, Bajaj Gopal
Keywords
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