Importance of Histopathology in Routine Cholecystectomies
Journal Title: Indian Journal of Pathology and Oncology - Year 2017, Vol 4, Issue 2
Abstract
Introduction: Gall bladder is one of the common histopathological specimen received in pathology department during routine practice. Many a times premaligant changes, in-situ and invasive carcinomas are found as incidental findings in histopathology (HPE). Objectives: To know the incidence of various histopathological lesions which are most of the times incidentally identified in routine and elective cholecystectomies at our institution. Materials and Method: The study was conducted from January 2016 to June 2016. The gross specimen of gall bladder was received for histopathological examination at department of pathology. Gross examination findings of the specimen were recorded. If any calculi were present, their type and number were documented. Eight bits were sampled with 4 bits in one capsule. Results: 107 gall bladder specimens were received during the study period. A female preponderance was seen in our study with male to female ratio of 1:2.2. Majority of the cases seen were between 31-40 yrs. 97.3% cases were non neoplastic lesion and 2.7% were neoplastic. 18 cases had metaplasia, out of which 13 cases (12.1%) showed antral type metaplasia, 2 cases (1.9%) of intestinal metaplasia and 3 cases (2.8%) with both antral and intestinal type metaplasia was seen. One case of biliary intra epithelial neoplasia grade II (0.9%), one case of biliary adenoma (0.9%) and one case of invasive adenocarcinoma of gall bladder (0.9%) were incidentally identified. Conclusion: Although most of the cholecystectomies are elective done for cholecystitis a varied histopathological types of the lesions can be seen in gall bladder. Thus a meticulous and detailed examination of both gross and microscopy by sampling more bits is essential. Hence routine histopathological examination is gold standard and is mandatory for all cholecystectomy specimens.
Authors and Affiliations
Ashwini B. R. , Hafsa Saif, Siddiq M. Ahmed
Keywords
Related Articles
- EP ID EP313024
- DOI 10.18231/2394-6792.2017.0064
- Views 57
- Downloads 0
Anemia in Type 2 Diabetes Mellitus (T2dm) and its association with vitamin B12 deficiency
Introduction India is the diabetic capital of the world Vitamin B12 deficiency has been recognized since many years ago as an important side effect in diabetic patients who take metformin for more than 510 yearsThis rese...
Clinicopathological study of neoplastic and non-neoplastic lesions of prostate- two years study
Introduction: Among the cancer related deaths in men, prostatic cancer is the second most common to lung cancer. Important cause for prostatic morbidity and mortality includes inflammation, benign nodular enlargement and...
A study of patterns of anemia in hospitalized infants at a tertiary care hospital
Introduction: Anemia can negatively affect cognitive development, school performance, physical growth and immunity of the children if not treated during infancy. Objectives: To determine the pattern of anemia among 6 mon...
Analysis of metastatic bone disease in a tertiary care centre
Introduction Metastasis to the bone is the third commonest site next to lung and liver It is one of the leading cause of morbidity and mortality in the world being an important prognostic indicator in advanced cancers Th...
Use of platelete concentrates in thrombocytopenia patients - A Hospital Based study of 138 cases
Background: Platelet transfusion is one of the most crucial therapeutic approaches in Medicine. In addition to their important function in hemostasis, platelet’s role in inflammation has become more evident. Also they ha...