Influence of Altiazem PP-180 on Hemodynamic Parameters in Arterial Hypertension Patients under Outpatient Conditions
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2017, Vol 6, Issue 10
Abstract
The aim of this research work is to study the effect of altiazem PP-180 on hemodynamic parameters in 78 II-degree arterial hypertension patients under outpatient conditions. Hemodynamic effect of altiazem PP-180 hypotensive action was successfully observed at 07.00 a.m., 10.00 a.m. and 10.00 p.m. intake time, with normal patients’ routine. Altiazem PP-180 causes a distinct hypotensive effect in II-degree arterial hypertension patients when used under outpatient conditions at different times of a day both fxed or random. The most productive hemodynamic effect of altiazem PP-180 hypotensive action can be observed when taken at 07.00 a.m., 10.00 a.m. and 10.00 p.m. provided that a normal work/rest routine is kept. When administered at 07.00 a.m., 10.00 a.m. and 10.00 p.m., altiazem PP-180 causes substantial decrease of peripheral vascular resistance, end-diastolic and end-systolic volumes. Hypotensive effect of altiazem PP-180, when administered at 01.00, 04.00 and 07.00 p.m. as well as at non-fxed times of day shows a less favourable hemodynamic effect: reduced cardiac output associated with total and peripheral vascular resistance index.
Authors and Affiliations
GR Zhakiyeva| Associate Professor and HOD, General Practice of Internship and Postgraduate Training, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan Corresponding e-mail: gulzhahan.zhakieva@list.ru, LM Tulegenova| Professor, Department of General Practice of Internship and Postgraduate Training, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan, NZ Ibragimova| Assistant Professor, Department of General Practice of Internship and Postgraduate Training, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan, SM Kelimberdiyev| Professor, Department of General Practice of Internship and Postgraduate Training, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan, KK Tokbayeva| Assistant Professor, Department of General Practice of Internship and Postgraduate Training, West Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan
Keywords
Related Articles
- EP ID EP12479
- DOI -
- Views 352
- Downloads 14
THE CHARACTERISTICS AND DETERMINANTS OF MAXIMAL EXPIRATORY PRESSURE IN YOUNG ADULTS FROM TRIPURA
Objective: To obtain values for normal maximal expiratory pressure (MEP) in adolescent subjects (age 17-21yrs) of Tripura and to correlate the normal values of MEP with different anthropometric and respiratory parameter...
CONSOLIDATE EFFECT OF VIBHAGHA PRANAYAMA, NADISHUDDI PRANAYAMA, SAVITHIRI PRANAYAMA AND KAPALABHATI PRANAYAMA ON THE PULMONARY FUNCTIONAL STATUS OF YOUNG HEALTHY MALE SUBJECTS
Introduction: Pranayama is believed to increase the respiratory stamina, relax the chest muscles, expand the lungs, raise energy levels, calm the body and cause over-all improvement in lung functions. In the present st...
Investigating students’ attitude and performance of smoking at Hormozgan University of Medical Sciences in 2015
Background and purpose of the study: Willingness to smoke and the negative consequences of smoking are among the main problems in general health all around the world. Therefore, the present research attempted to investi...
INTRA UTERINE INSEMINATION AN EXPERIENCE IN RURAL POPULATION
Objective:1) To find out efficacy of various ovulation induction protocols in IUI 2) To find out the efficacy of IUI in treatment of infertility Method: All infertility patients of our OPD underwent a standard investig...
BILATERAL INTERNUCLEAR OPHTHALMOPLEGIA AS FIRST MANIFESTATION OF EXTRA PONTINE MYELINOLYSIS
Extrapontine myelinolysis (EPM) is a rare clinical entity affecting anterior basal ganglia. This is one of the osmotic demyelination syndromes. It occurs due to rapid correction of hyponatremia and also rarely occurs in...